593273

1,5-Diacetylindoline

97%

• Empirical Formula (Hill Notation): C₁₂H₁₃NO₂
• CAS Number: 16078-35-6
• Molecular Weight: 203.24
• MDL number: MFCD00459527
• UNSPSC Code: 12352100
• PubChem Substance ID: 24881432
• NACRES: NA.22

Properties

• assay: 97%
• form: solid
• mp: 137-141 °C (lit.)
• SMILES string: CC(=O)N1CCc2cc(ccc12)C(C)=O
• InChI: 1S/C12H13NO2/c1-8(14)10-3-4-12-11(7-10)5-6-13(12)9(2)15/h3-4,7H,5-6H2,1-2H3
• InChI key: DDTZNSOMVMYKHA-UHFFFAOYSA-N

Description

Application

• Reactant for α-arylation reactions
• Reactant for preparation of 5-HT1B receptor antagonists
• Reactant for synthesis of N-(1-benzo[1,3]dioxol-5-yl)ethyl-, N-[1-(2,3-dihydro-benzofuran-5-yl)ethyl-, and N-[1-(2,3-dihydro-1H-indol-5-yl)ethylacrylamides as KCNQ2 opener agents
• Reactant for preparation of 1-acyl-7-nitroindolines as L-glutamate photoreleasing agents in cerebellar granule neurons

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves