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47637

Sigma-Aldrich

Fmoc-Trp-OH

≥97.0% (HPLC)

Synonym(s):

Fmoc-L-tryptophan

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About This Item

Empirical Formula (Hill Notation):
C26H22N2O4
CAS Number:
35737-15-6
Molecular Weight:
426.46
Beilstein/REAXYS Number:
4216624
EC Number:
252-706-5
MDL number:
MFCD00037126
UNSPSC Code:
12352200
eCl@ss:
32160406
PubChem Substance ID:
57651054
NACRES:
NA.26

assay

≥97.0% (HPLC)

optical activity

[α]20/D −29±1°, c = 1% in DMF

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

mp

182-185 °C (lit.)

application(s)

peptide synthesis

functional group

Fmoc

storage temp.

2-8°C

SMILES string

OC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)OCC3c4ccccc4-c5ccccc35

InChI

1S/C26H22N2O4/c29-25(30)24(13-16-14-27-23-12-6-5-7-17(16)23)28-26(31)32-15-22-20-10-3-1-8-18(20)19-9-2-4-11-21(19)22/h1-12,14,22,24,27H,13,15H2,(H,28,31)(H,29,30)/t24-/m0/s1

InChI key

MGHMWKZOLAAOTD-DEOSSOPVSA-N

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Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
BCBW5292
BCBQ0489V
BCBL4273V
BCBB4723V
BCBB4723

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Sigma-Aldrich

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Sigma-Aldrich

531480

Fmoc-Ala-OH

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Huntington's disease (HD) is classified as a protein-misfolding disease correlated with the mutant Huntingtin (mHtt) protein with abnormally expanded polyglutamine (polyQ) domains. Because no effective drugs have yet been reported, attempts to develop better therapy to delay the age of
Chloé Guilbaud-Chéreau et al.
ACS applied materials & interfaces, 11(14), 13147-13157 (2019-03-14)
Molecular gels formed by the self-assembly of low-molecular-weight gelators have received increasing interest because of their potential applications in drug delivery. In particular, the ability of peptides and amino acids to spontaneously self-assemble into three-dimensional fibrous network has been exploited
Chiao-Ting Yen et al.
European journal of medicinal chemistry, 44(5), 1933-1940 (2008-12-27)
Twenty-four new dipeptide analogs (1-24) of aurantiamide acetate were designed, synthesized, and assayed for effects on superoxide anion generation and elastase release by human neutrophils in response to fMLP/CB. Among them, seven N-(fluorenyl-9-methoxycarbonyl) (Fmoc)-dipeptides (6, 9, 12, 14, 17, 18

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