419370
3,4-Dihydroxybenzaldehyde
synthesis grade
Synonym(s):
Protocatechualdehyde
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About This Item
Linear Formula:
(HO)2C6H3CHO
CAS Number:
Molecular Weight:
138.12
Beilstein/REAXYS Number:
774381
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
grade
synthesis grade
mp
150-157 °C (lit.)
SMILES string
Oc1ccc(C=O)cc1O
InChI
1S/C7H6O3/c8-4-5-1-2-6(9)7(10)3-5/h1-4,9-10H
InChI key
IBGBGRVKPALMCQ-UHFFFAOYSA-N
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Description
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signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Chang Yoon Moon et al.
Biochemical and biophysical research communications, 423(1), 116-121 (2012-05-30)
The migration and proliferation of vascular smooth muscle cells (VSMCs) and formation of intravascular thrombosis play crucial roles in the development of atherosclerotic lesions. This study examined the effects of protocatechuic aldehyde (PCA), a compound isolated from the aqueous extract
Jin Boo Jeong et al.
Biochemical and biophysical research communications, 430(1), 381-386 (2012-11-20)
Protocatechualdehyde (PCA) is a naturally occurring polyphenol found in barley, green cavendish bananas, and grapevine leaves. Although a few studies reported growth-inhibitory activity of PCA in breast and leukemia cancer cells, the underlying mechanisms are still poorly understood. Thus, we
Bo-bo Chang et al.
Acta pharmacologica Sinica, 31(5), 638-646 (2010-04-07)
To investigate the pharmacokinetic interactions induced by content variation of the main water-soluble components of Danshen injection in rats. Intravenous Danshen injection (control) or Danshen injection with danshensu (DSS), protocatechuic aldehyde (PAL), salvianolic acid A (Sal A) or salvianolic acid
Narsimha Mamidi et al.
The journal of physical chemistry. B, 116(35), 10684-10692 (2012-08-07)
Diacylglycerol (DAG) regulates a broad range of cellular functions including tumor promotion, apoptosis, differentiation, and growth. Thus, the DAG-responsive C1 domain of protein kinase C (PKC) isoenzymes is considered to be an attractive drug target for the treatment of cancer
Yong Xu et al.
Basic & clinical pharmacology & toxicology, 110(4), 384-389 (2011-11-05)
Recent studies have demonstrated that nuclear factor-κB (NF-κB) and high-mobility group box 1 (HMGB1) are associated with the pathophysiology of sepsis. The present study was carried out to investigate the effects of protocatechuic aldehyde (PA) on an experimental model of
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