Skip to Content
MilliporeSigma
All Photos(1)

Key Documents

View All Documentation

370622

Sigma-Aldrich

4-(Trifluoromethoxy)benzyl bromide

97%

Sign Into View Organizational & Contract Pricing

Select a Size

1 G
$82.55
5 G
$131.10

$82.55

List Price$86.90Save 5%
Web-Only Promotion

Available to ship onApril 18, 2025Details

Request a Bulk Order
All Photos(1)

Select a Size

Change View
1 G
$82.55
5 G
$131.10

About This Item

Linear Formula:
CF3OC6H4CH2Br
CAS Number:
50824-05-0
Molecular Weight:
255.03
MDL number:
MFCD00061238
UNSPSC Code:
12352100
PubChem Substance ID:
24863081
NACRES:
NA.22

$82.55

List Price$86.90Save 5%
Web-Only Promotion

Available to ship onApril 18, 2025Details

Request a Bulk Order

assay

97%

form

liquid

refractive index

n20/D 1.48 (lit.)

bp

82-84 °C/10 mmHg (lit.)

density

1.594 g/mL at 25 °C (lit.)

functional group

bromo
fluoro

SMILES string

FC(F)(F)Oc1ccc(CBr)cc1

InChI

1S/C8H6BrF3O/c9-5-6-1-3-7(4-2-6)13-8(10,11)12/h1-4H,5H2

InChI key

JDNPUJCKXLOHOW-UHFFFAOYSA-N

Related Categories

General description

Polymerizations of 4-(trifluoromethoxy)benzyl bromide, via Friedel-Crafts polymerization using aluminum chloride as a catalyst has been reported.[1]

Application

4-(Trifluoromethoxy)benzyl bromide may be used in the synthesis of bioreductive drug, (6S)-2-nitro-6-{[4-(trifluoromethoxy)benzyl]oxy}-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine (PA-824).[2]

pictograms

Corrosion
GHS05

signalword

Danger

hcodes

H314

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1B

Storage Class

8A - Combustible corrosive hazardous materials

wgk_germany

WGK 3

flash_point_f

201.2 °F - closed cup

flash_point_c

94 °C - closed cup

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
MKCT1449
MKBV7766V
MKBR5064V
MKBQ7082V
MKBN2884V

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Andrew M Thompson et al.
Journal of medicinal chemistry, 52(3), 637-645 (2008-12-23)
The nitroimidazooxazine S-1 (PA-824) is a new class of bioreductive drug for tuberculosis. A series of related bicyclic nitroheterocycles was synthesized, designed to have a wide range of one-electron reduction potentials E(1) (from -570 to -338 mV, compared with -534
Synthesis and properties of fluorine-containing poly (arylenemethylene) s as new heat resistant denatured phenolic resins.
Nemoto T, et al.
Polymer Journal, 40(7), 622-628 (2008)

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service