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295590

Sigma-Aldrich

Nitrous oxide

99%

Synonym(s):

Dinitrogen monoxide, Laughing gas

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227 G
$431.03

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227 G
$431.03

About This Item

Empirical Formula (Hill Notation):
N2O
CAS Number:
Molecular Weight:
44.01
Beilstein/REAXYS Number:
8137358
EC Number:
MDL number:
UNSPSC Code:
12142100
PubChem Substance ID:
NACRES:
NA.22

$431.03

List price$468.00Save 8%
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Available to ship onApril 08, 2025Details


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vapor density

1.53 (15 °C, vs air)

Quality Level

vapor pressure

51.7 mmHg ( 21 °C)

assay

99%

bp

−88 °C (lit.)

mp

−91 °C (lit.)

SMILES string

[O-][N+]#N

InChI

1S/N2O/c1-2-3

InChI key

GQPLMRYTRLFLPF-UHFFFAOYSA-N

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Application

  • Nitrous oxide allows selective oxygen atom transfer reactions while minimizing the risk of over-oxidation.[1] Therefore, it is used to oxidize disilenes, silanimines, silaethenes and silylenes.[1]
  • Along with Ru-porphyrin catalyst, it can be used in the epoxidation of olefins and steroids.[2]
  • It can be used as an oxidant in for the metal-catalyzed oxidative homo- and cross-coupling of Grignard reagents.[3]
  • N2O can also be used as a nitrogen-dopant source to synthesize p-type zinc oxide nanowires (ZnO NWs) via vapor-liquid-solid growth.[4]

Packaging

Supplied in a carbon steel lecture bottle with a CGA180M/CGA110F needle valve installed.

Compatible with the following:
  • Aldrich® lecture-bottle station systems
  • Aldrich® lecture-bottle gas regulators

Other Notes

Legal Information

Aldrich is a registered trademark of Sigma-Aldrich Co. LLC

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purge valve

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Danger

Hazard Classifications

Ox. Gas 1 - Press. Gas Liquefied gas - STOT SE 3

target_organs

Central nervous system

Storage Class

2A - Gases

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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Synthetic chemistry with nitrous oxide.
Severin K.
Chemical Society Reviews, 44(17), 6375-6386 (2015)
Nitrous oxide oxidation of olefins catalyzed by ruthenium porphyrin complexes.
Yamada T, et al.
Chemistry Letters (Jpn), 30(3), 268-269 (2001)
Git Lidman et al.
Developmental medicine and child neurology, 57(8), 754-761 (2015-03-27)
To investigate the effects of repeated botulinum toxin A (BoNT-A) injections combined with occupational therapy, including a splint, compared with occupational therapy alone on hand function in children with unilateral spastic cerebral palsy (USCP), in all International Classification of Functioning
Oxidative Coupling Reactions of Grignard Reagents with Nitrous Oxide.
Kiefer G, et al.
Angewandte Chemie (International Edition in English), 52(24), 6302-6305 (2013)
Klaus Butterbach-Bahl et al.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 368(1621), 20130122-20130122 (2013-05-29)
Although it is well established that soils are the dominating source for atmospheric nitrous oxide (N2O), we are still struggling to fully understand the complexity of the underlying microbial production and consumption processes and the links to biotic (e.g. inter-

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    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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