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293369

Sigma-Aldrich

3-Aminopiperidine dihydrochloride

97%

Synonym(s):

3-Piperidinamine dihydrochloride

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About This Item

Empirical Formula (Hill Notation):
C5H12N2 · 2HCl
Molecular Weight:
173.08
MDL number:
MFCD00012773
UNSPSC Code:
12352100
PubChem Substance ID:
24857652

assay

97%

form

solid

mp

230 °C (dec.) (lit.)

SMILES string

Cl.Cl.NC1CCCNC1

InChI

1S/C5H12N2.2ClH/c6-5-2-1-3-7-4-5;;/h5,7H,1-4,6H2;2*1H

InChI key

GGPNYXIOFZLNKW-UHFFFAOYSA-N

General description

Estimation of (S)-piperidin-3-amine in (R)-piperidin-3-amine dihydrochloride (3-aminopiperidine dihydrochloride) has been investigated by chiral high-performance liquid chromatographic (chiral HPLC) method.

Application

Reactant for N-arylation of heterocyclic diamines

Reactant for synthesis of substituted quinolones with reduced phototoxic risk

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Shubo Dong et al.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 33(3), 293-298 (2017-03-18)
A sensitive non-derivatization method for the determination of the highly polar compound 3-aminopiperidine was developed using a mixed-mode column combined with a charged aerosol detector (CAD). Chromatographic conditions, including the type of detector, separation mode, and mobile phase composition, were
Chittabathina Venkata Raghunadha Babu et al.
Chirality, 26(12), 775-779 (2014-07-22)
A simple, precise, accurate, robust chiral high-performance liquid chromatographic (chiral HPLC) method was developed for estimation of (S)-piperidin-3-amine (S-isomer) in (R)-piperidin-3-amine dihydrochloride (R-AMP). As AMP is a high-melting solid and nonchromophoric compound, development of a suitable chiral method is a

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