283495

5-Bromo-2-fluorotoluene

97%

• Linear Formula: CH₃C₆H₃(Br)F
• CAS Number: 51437-00-4
• Molecular Weight: 189.02
• Beilstein/REAXYS Number: 2242693
• EC Number: 257-202-9
• MDL number: MFCD00000343
• UNSPSC Code: 12352100
• PubChem Substance ID: 24857109

Properties

• assay: 97%
• refractive index: n20/D 1.529 (lit.)
• density: 1.486 g/mL at 25 °C (lit.)
• functional group: bromo; fluoro
• SMILES string: Cc1cc(Br)ccc1F
• InChI: 1S/C7H6BrF/c1-5-4-6(8)2-3-7(5)9/h2-4H,1H3
• InChI key: VXKYOKPNAXNAFU-UHFFFAOYSA-N

Description

Application

5-Bromo-2-fluorotoluene has been used in the preparation of:

• 5-bromo-2-fluorobenzyl bromide via N-bromosuccinimide (NBS) bromination, required for the synthesis of crown bromofluorobenzene
• 3-(4-fuoro-3-methylphenyl)acrylamide

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 3
• flash_point_f: 163.4 °F - closed cup
• flash_point_c: 73 °C - closed cup
• ppe: Eyeshields, Gloves, type ABEK (EN14387) respirator filter