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268054

Sigma-Aldrich

Tetracycline hydrate

99%

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About This Item

Empirical Formula (Hill Notation):
C22H24N2O8 · xH2O
CAS Number:
305833-60-7
Molecular Weight:
444.43 (anhydrous basis)
EC Number:
200-481-9
MDL number:
MFCD09749819
UNSPSC Code:
12352115
PubChem Substance ID:
24856259

assay

99%

optical activity

[α]25/D −255°, c = 1 in 0.1 M HCl

mp

175-177 °C (lit.)

SMILES string

O.CN(C)[C@H]1[C@@H]2C[C@H]3C(=C(O)[C@]2(O)C(=O)C(C(N)=O)=C1O)C(=O)c4c(O)cccc4[C@@]3(C)O

InChI

1S/C22H24N2O8.H2O/c1-21(31)8-5-4-6-11(25)12(8)16(26)13-9(21)7-10-15(24(2)3)17(27)14(20(23)30)19(29)22(10,32)18(13)28;/h4-6,9-10,15,25,27-28,31-32H,7H2,1-3H3,(H2,23,30);1H2/t9-,10-,15-,21+,22-;/m0./s1

InChI key

ZRRILXUKODPUEN-FMZCEJRJSA-N

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2 - Repr. 2

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  4. What is meant by xH20 in the structure of Product 268054, Tetracycline hydrate?

    This indicates that there is an indeterminate number of water molecules present per molecule of the compound.

  5. What is the expected appearance of Product 268054, Tetracycline hydrate?

    The product is a yellow powder.

  6. At what temperature should Product 268054, Tetracycline hydrate, be stored?

    The material should be stored at room temperature.

  7. What solvent can Product 268054, Tetracycline hydrate, be dissolved in?

    This product is soluble up to 50mg/mL in 1N HCl, yielding a clear to slightly hazy yellow to orange-brown solution. Lot No. 01423MH was found to be soluble at 50 mg/mL in 1N HCl.

  8. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  9. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

Federica Martini et al.
TheScientificWorldJournal, 2012, 605804-605804 (2012-05-26)
Biologically active substances could reach the aquatic compartment when livestock wastes are considered for recycling. Recently, the standardized FETAX assay has been questioned, and some researchers have considered that the risk assessment performed on fish could not be protective enough
Bijay Kumar Jha et al.
Parasitology research, 114(3), 1189-1195 (2015-01-08)
Acanthamoeba is an opportunistic protozoan parasite responsible for different diseases in humans, such as granulomatous amoebic encephalitis and amoebic keratitis. Tigecycline, a third-generation tetracycline antibiotic, has potential activity to treat most of the antibiotic resistant bacterial infections. The effects of

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