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Sigma-Aldrich

Sodium 3-mercapto-1-propanesulfonate

technical grade, 90%

Synonym(s):

3-Mercapto-1-propanesulfonic acid sodium salt, MPS

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About This Item

Linear Formula:
HSCH2CH2CH2SO3Na
CAS Number:
17636-10-1
Molecular Weight:
178.21
Beilstein/REAXYS Number:
5362242
EC Number:
241-620-3
MDL number:
MFCD00043148
UNSPSC Code:
12352100
PubChem Substance ID:
24855149
NACRES:
NA.22

grade

technical grade

assay

90%

form

powder

mp

~220 °C (dec.) (lit.)

solubility

water: soluble 50 mg/mL, colorless

SMILES string

[Na+].[O-]S(=O)(=O)CCCS

InChI

1S/C3H8O3S2.Na/c4-8(5,6)3-1-2-7;/h7H,1-3H2,(H,4,5,6);/q;+1/p-1

InChI key

FRTIVUOKBXDGPD-UHFFFAOYSA-M

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General description

Sodium 3-mercapto-1-propanesulfonate forms self assembled monolayer via chemisorption on a gold-coated substrate.

Application

Sodium 3-mercapto-1-propanesulfonate (MPS) can be used to prepare tetrasubstituted organosilicon thioether by photochemical reaction with tetravinylsilane via thiol-ene reaction. It can also be used as a capping agent to functionalize gold nanoparticles for potential applications in the field of radiotherapy and drug delivery.
MPS can be also used in the preparation of Rh nanoparticles by liquid-phase reduction of rhodium (III) chloride.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

159.8 °F - closed cup

flash_point_c

71 °C - closed cup

ppe

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Nucleobases functionalized quantum dots and gold nanoparticles bioconjugates as a fluorescence resonance energy transfer (FRET) system-Synthesis, characterization and potential applications
Rodzik-Czalka L, et al.
Journal of Colloid and Interface Science, 514(20), 479-490 (2018)
Naoyuki Sakamoto et al.
Nanoscale, 1(1), 106-109 (2010-07-21)
Highly dispersed rhodium nanoparticles (1.7 +/- 0.3 nm) prepared by a liquid-phase reduction method were loaded on a solid solution of GaN and ZnO without forming aggregates, achieving improved activity for visible-light-driven overall water splitting when the nanoparticles are coated
Mieke Aldenhoven et al.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 21(6), 1106-1109 (2015-02-25)
Allogeneic hematopoietic cell transplantation (HCT) is the only treatment able to prevent progressive neurodegenerative disease in a selected group of mucopolysaccharidosis (MPS) disorders. However, its use was historically limited by the high risk of graft failure and transplantation-related morbidity and
Synthesis of functionalized gold nanoparticles capped with 3-mercapto-1-propansulfonate and 1-thioglucose mixed thiols and ?in vitro? bioresponse
Porcaro F, et al.
Colloids and Surfaces. B, Biointerfaces, 142(20), 408-416 (2016)
Thiol- Ene Reaction for the Synthesis of Multifunctional Branched Organosilanes
Rissing C and Son DY
Organometallics, 27(20), 5394-5397 (2008)
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