218693
1-Aminocyclohexanecarboxylic acid
98%
Synonym(s):
Homocycloleucine
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All Photos(1)
About This Item
Linear Formula:
H2NC6H10CO2H
CAS Number:
Molecular Weight:
143.18
Beilstein/REAXYS Number:
2355692
EC Number:
MDL number:
UNSPSC Code:
12352106
PubChem Substance ID:
NACRES:
NA.22
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assay
98%
form
solid
reaction suitability
reaction type: solution phase peptide synthesis
mp
>300 °C (lit.)
application(s)
peptide synthesis
SMILES string
NC1(CCCCC1)C(O)=O
InChI
1S/C7H13NO2/c8-7(6(9)10)4-2-1-3-5-7/h1-5,8H2,(H,9,10)
InChI key
WOXWUZCRWJWTRT-UHFFFAOYSA-N
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Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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B Jastrzebska et al.
The journal of peptide research : official journal of the American Peptide Society, 62(2), 70-77 (2003-06-26)
In this study we describe the synthesis and some pharmacological properties of seven new analogues of arginine vasopressin (AVP) substituted in position 2 or 3 with 1-aminocyclohexane-1-carboxylic acid (Acc). All peptides were tested for the pressor, antidiuretic and uterotonic in
Francisco Rodríguez-Ropero et al.
Journal of chemical information and modeling, 48(2), 333-343 (2008-01-19)
Conformationally restricted amino acids are promising candidates to serve as basic pieces in redesigned protein motifs which constitute the basic modules in synthetic nanoconstructs. Here we study the ability of constrained cyclic amino acid 1-aminocyclohexane-1-carboxylic acid (Ac6c) to stabilize highly
Olga Labudda et al.
Journal of peptide science : an official publication of the European Peptide Society, 12(12), 775-779 (2006-11-30)
A sterically constrained non-coded amino acid, 1-aminocyclopentane-1-carboxylic acid (Apc), was introduced in position 7 or 8 of the bradykinin (BK) B(2) receptor antagonist, [D-Arg(0), Hyp(3), Thi(5, 8), D-Phe(7)]BK, previously synthesized by Stewart's group. This modification is believed to reduce the
Nicolas Fabresse et al.
Journal of pharmaceutical and biomedical analysis, 141, 149-156 (2017-04-27)
Tranexamic acid is a widely used antifibrinolytic drug but its pharmacology and pharmacokinetics remains poorly understood. Owing to the recent knowledge on phospholipid-induced matrix effects during human plasma analysis, our aim was to develop a liquid chromatography-mass spectrometry method for
Wioleta Kowalczyk et al.
Journal of medicinal chemistry, 47(24), 6020-6024 (2004-11-13)
The synthesis and some pharmacological properties of two sets of analogues, one consisting of six peptides with 1-aminocyclohexane-1-carboxylic acid (Acc) in position 2 and the other with the amino acid in position 3, have been described. All the peptides were
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