Skip to Content
MilliporeSigma
All Photos(2)

Key Documents

View All Documentation

217077

Sigma-Aldrich

6-Hydroxy-1,3-benzoxathiol-2-one

≥98%

Synonym(s):

Tioxolone

Sign Into View Organizational & Contract Pricing

Select a Size

50 G
$143.00

$143.00

List Price$286.00Save 50%

In StockDetails

Request a Bulk Order
All Photos(2)

Select a Size

Change View
50 G
$143.00

About This Item

Empirical Formula (Hill Notation):
C7H4O3S
CAS Number:
4991-65-5
Molecular Weight:
168.17
EC Number:
225-653-0
MDL number:
MFCD00005859
UNSPSC Code:
12352100
PubChem Substance ID:
24852991
NACRES:
NA.22

$143.00

List Price$286.00Save 50%

In StockDetails

Request a Bulk Order

Quality Level

100

assay

≥98%

mp

158-160 °C (lit.)

solubility

95% ethanol: soluble 50 mg/mL, clear to very slightly hazy, colorless to yellow
benzene: soluble
diethyl ether: soluble
isopropanol: soluble
propylene glycol: soluble
toluene: soluble
water: insoluble

SMILES string

Oc1ccc2SC(=O)Oc2c1

InChI

1S/C7H4O3S/c8-4-1-2-6-5(3-4)10-7(9)11-6/h1-3,8H

InChI key

SLYPOVJCSQHITR-UHFFFAOYSA-N

General description

Antimicrobial and cytostatic properties of 6-hydroxy-1,3-benzoxathiol-2-one has been investigated[1]. Supramolecular structure of 6-hydroxy-1,3-benzoxathiol-2-one has been studied[2].

Application

6-Hydroxy-1,3-benzoxathiol-2-one was used in the synthesis of heterocycle-phosphor esters having potential antimicrobial activity[3].

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
STBC0142V
STBC1485V
00619LH
04417DH
02904DE

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Alessio Innocenti et al.
Bioorganic & medicinal chemistry letters, 18(14), 3938-3941 (2008-06-24)
Inhibition of 13 mammalian isoforms of the metalloenzyme carbonic anhydrase (CA, EC 4.2.1.1), CA I-XV, with thioxolone (6-hydroxy-1,3-benzoxathiol-2-one) and two sulfonamides was investigated. Thioxolone was inefficient for generating isozyme-selective inhibitors, since except for CA I which is inhibited in the
Maureen Byres et al.
Acta crystallographica. Section C, Crystal structure communications, 60(Pt 6), o395-o396 (2004-06-05)
The planar molecules of 6-hydroxy-1,3-benzoxathiol-2-one, C(7)H(4)O(3)S, are linked by extensive O-H.O and C-H.O hydrogen bonding and are further stablilized by face-to-face pi-pi interactions.
Contact dermatitis from thioxolone.
F Villas Martinez et al.
Contact dermatitis, 29(2), 96-96 (1993-08-01)
[Antimicrobial and cytostatic properties of 6-hydroxy-1,3-benzoxathiol-2-one (01 1)].
H Goeth et al.
Arzneimittel-Forschung, 19(8), 1298-1304 (1969-08-01)
Contact dermatitis to thioxolone.
J G Camarasa
Contact dermatitis, 7(4), 213-214 (1981-07-01)
View All Related Papers

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service