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202339

Sigma-Aldrich

Poly(propylene glycol)

average Mn ~2,000

Synonym(s):

PPG, Poly(propylene oxide)

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About This Item

Linear Formula:
H[OCH(CH3)CH2]nOH
CAS Number:
25322-69-4
MDL number:
MFCD00084446
UNSPSC Code:
12162002
PubChem Substance ID:
24852056
NACRES:
NA.23

vapor density

>1 (vs air)

vapor pressure

<0.01 mmHg ( 20 °C)

mol wt

average Mn ~2,000

contains

130-190 ppm proprietary phenolic antioxidant

refractive index

n20/D 1.451

viscosity

300 cSt(25 °C)(lit.)

hydroxyl value

56 mg KOH/g

density

1.005 g/mL at 25 °C

SMILES string

CC(O)CO

InChI

1S/C6H14O3/c1-5(8)4-9-6(2)3-7/h5-8H,3-4H2,1-2H3

InChI key

DUFKCOQISQKSAV-UHFFFAOYSA-N

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General description

Poly(propylene glycol) (PPG) is a polyether. It is prepared by ring-opening polymerization of propylene oxide. PPG is less toxic and used as a dispersant in leather finishing, as a surfactant, wetting agent, and in drug formulations.

Application

Poly(propylene glycol) can be used as a:
  • Corrosion inhibitor for mild steel in acid solution.
  • Starting material to synthesize epoxy resin/polyurethane hybrid networks via frontal polymerization.
It can also be used to prepare poly(PEG/PPG/PTMC urethane) thermogels for sustained release of doxorubicin.

Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

445.0 °F - closed cup

flash_point_c

229.44 °C - closed cup

ppe

Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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John Texter et al.
Macromolecular rapid communications, 33(1), 69-74 (2011-12-03)
The controlled atom transfer radical polymerization of an ionic liquid, 1-(11-acryloylundecyl)-3-methyl imidazolium bromide (ILBr), from both ends of a telechelic poly(propylene oxide) (PPO) macroinitiator, end-functionalized with bromoisobutyryloyl is reported. The resulting highly water-soluble triblock, poly(ILBr-b-PO-b-ILBr) is multistimuli responsive. This new
Celeste R Brennecka et al.
World neurosurgery, 78(5), 469-480 (2011-11-29)
Current treatments for cerebral aneurysms are far from ideal. Platinum coils are prone to compaction, and currently used liquid embolics are delivered with angiotoxic agents. This work presents initial in vivo studies of a novel liquid-to-solid gelling polymer system (PPODA-QT)
R De Lisi et al.
Physical chemistry chemical physics : PCCP, 13(27), 12571-12577 (2011-06-15)
The study highlighted the main forces driving the formation of hydroxypropyl-cyclodextrins (HP-CDs) + poly(propylene) glycol 725 g mol(-1) inclusion complexes. The temperature parameter was chosen as the variable to modulate the hydrophobicity of the polymer, and consequently ITC experiments as
Flávia Chiva Carvalho et al.
Journal of biomedical nanotechnology, 8(2), 280-289 (2012-04-21)
In the last few decades, nanotechnology has led to an advance in the development of topical drug delivery. Nanostructured drug delivery systems enable the compartmentalization of drugs in restricted environments, modifying the release profile and maintaining the required drug concentration
Mohammed Taghi Zafarani-Moattar et al.
Biotechnology progress, 28(1), 146-156 (2011-09-29)
In this work, we proposed a novel aqueous biphasic system (ABS) composed of polypropylene glycol P400 (PPG P400) and hydrophilic ionic liquids (IL), 1-alkyl-3-methylimidazolium bromide (alkyl = ethyl or butyl), forming an upper polymer-rich phase and a lower IL-rich phase
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