17356

3-(Boc-amino)propyl bromide

≥96.0% (GC)

• Synonym(s): tert-Butyl N-(3-bromopropyl)carbamate
• Linear Formula: Br(CH₂)₃NHCO₂C(CH₃)₃
• CAS Number: 83948-53-2
• Molecular Weight: 238.12
• Beilstein/REAXYS Number: 4176344
• MDL number: MFCD02683429
• UNSPSC Code: 12352200
• PubChem Substance ID: 57647642
• NACRES: NA.22

Properties

• Quality Level: 200
• assay: ≥96.0% (GC)
• reaction suitability: reagent type: cross-linking reagent
• mp: 37-39 °C
• functional group: Boc; amine; bromo
• storage temp.: 2-8°C
• SMILES string: BrCCCNC(OC(C)(C)C)=O
• InChI: 1S/C8H16BrNO2/c1-8(2,3)12-7(11)10-6-4-5-9/h4-6H2,1-3H3,(H,10,11)
• InChI key: IOKGWQZQCNXXLD-UHFFFAOYSA-N

Description

Application

3-(Boc-amino)propyl bromide can be used as an alkylating reagent for the synthesis of:

• Benzydamine analogs to be used as activators for soluble guanylate cyclase.[1]
• N-substituted chromenotriazolopyrimidine, human murine double minute 2 (MDM2) inhibitor.[2]
• Protected amines from piperidine derivatives to be further used for synthesis of sulfonamide series.[3]

It can also be used for the post-polymerization quaternization of polymers to synthesize functional cationic polymers and antimicrobial agents.[4]

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H302,H315,H319,H335
• pcodes: P261 - P264 - P271 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves