15408

N-Boc-1,3-propanediamine

≥97.0% (GC/NT)

• Synonym(s): N-Boc-1,3-diaminopropane, tert-Butyl N-(3-aminopropyl)carbamate
• Linear Formula: (CH₃)₃COCONH(CH₂)₃NH₂
• CAS Number: 75178-96-0
• Molecular Weight: 174.24
• Beilstein/REAXYS Number: 3588328
• MDL number: MFCD00210021
• UNSPSC Code: 12352116
• PubChem Substance ID: 57647415
• NACRES: NA.22

Properties

• Quality Level: 100
• assay: ≥97.0% (GC/NT)
• reaction suitability: reagent type: cross-linking reagent
• refractive index: n20/D 1.454 (lit.); n20/D 1.459
• bp: 203 °C (lit.)
• mp: 22 °C (lit.)
• density: 0.998 g/mL at 20 °C (lit.)
• functional group: Boc; amine
• SMILES string: NCCCNC(OC(C)(C)C)=O
• InChI: 1S/C8H18N2O2/c1-8(2,3)12-7(11)10-6-4-5-9/h4-6,9H2,1-3H3,(H,10,11)
• InChI key: POHWAQLZBIMPRN-UHFFFAOYSA-N

Description

Application

• Tackling vancomycin-resistant bacteria with ′lipophilic–vancomycin–carbohydrate conjugates′: This study discusses the synthesis of derivatives using N-Boc-1,3-propanediamine to develop new antibacterial agents targeting resistant bacterial strains (Yarlagadda et al., 2015).
• Sulfonamides differing in the alkylamino substituent length–Synthesis, electrochemical characteristic, acid-base profile and complexation properties: The study involves N-Boc-1,3-propanediamine in the synthesis of novel sulfonamide derivatives with potential biochemical applications (Ciesielska et al., 2022).
• Direct α-alkylation of primary aliphatic amines enabled by CO2 and electrostatics: Research demonstrating selective α-alkylation of N-Boc-1,3-propanediamine, highlighting a novel method in organic synthesis (Ye et al., 2018).

Other Notes

Synthesis of spermidine analogues; Preparation of pharmacologically active compounds.

Safety Information

• pictograms: GHS05,GHS07
• signalword: Danger
• hcodes: H302,H314
• pcodes: P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363
• Hazard Classifications: Acute Tox. 4 Oral - Skin Corr. 1B
• Storage Class: 8A - Combustible corrosive hazardous materials
• wgk_germany: WGK 3
• flash_point_f: 228.2 °F - closed cup
• flash_point_c: 109 °C - closed cup
• ppe: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter