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142239

1-Butyl-3-nitro-1-nitrosoguanidine

Name: 1-Butyl-3-nitro-1-nitrosoguanidine
Brand: ALDRICH

97%

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About This Item

Linear Formula:

CH₃(CH₂)₃N(NO)C(=NH)NHNO₂

CAS Number:

13010-08-7

Molecular Weight:

189.17

EC Number:

235-857-1

MDL number:

MFCD00007037

UNSPSC Code:

12352100

PubChem Substance ID:

24848387

assay

97%

mp

119-120 °C (dec.) (lit.)

SMILES string

CCCCN(N=O)C(=N)N[N+]([O-])=O

pictograms

GHS02,GHS08,GHS07

signalword

Danger

hcodes

H228,H315,H319,H335,H350

pcodes

P202 - P210 - P240 - P302 + P352 - P305 + P351 + P338 - P308 + P313

Hazard Classifications

Carc. 1B - Eye Irrit. 2 - Flam. Sol. 1 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

4.1B - Flammable solid hazardous materials

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type P2 (EN 143) respirator cartridges, type P3 (EN 143) respirator cartridges

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Repair and mutagenesis in Escherichia coli K-12 after exposure to various alkyl-nitrosoguanidines.

M L Todd et al.

Journal of bacteriology, 156(1), 6-12 (1983-10-01)

The mutagenic and toxic effects of a series of N-alkyl-N'-nitro-N-nitrosoguanidines were examined in Escherichia coli K-12. The role of nucleotide excision repair, the SOS response, and the adaptive response in both the reduction and the production of the biological effects

Construction and characterization of mutants of Salmonella typhimurium deficient in DNA repair of O6-methylguanine.

M Yamada et al.

Journal of bacteriology, 177(6), 1511-1519 (1995-03-01)

Escherichia coli has two O6-methylguanine DNA methyltransferases that repair alkylation damage in DNA and are encoded by the ada and ogt genes. The ada gene of E. coli also regulates the adaptive response to alkylation damage. The closely related species

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