Skip to Content
MilliporeSigma
All Photos(1)

Documents

132527

Sigma-Aldrich

(S)-(+)-2-Amino-1-butanol

≥98%

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
C2H5CH(NH2)CH2OH
CAS Number:
5856-62-2
Molecular Weight:
89.14
Beilstein/REAXYS Number:
1718930
EC Number:
227-475-9
MDL number:
MFCD00064418
UNSPSC Code:
12352116
PubChem Substance ID:
24848057
NACRES:
NA.22

assay

≥98%

form

liquid

optical activity

[α]20/D +10°, neat

optical purity

ee: 96% (GLC)

refractive index

n20/D 1.4521 (lit.)

bp

172-174 °C (lit.)

density

0.944 g/mL at 25 °C (lit.)

SMILES string

CC[C@H](N)CO

InChI

1S/C4H11NO/c1-2-4(5)3-6/h4,6H,2-3,5H2,1H3/t4-/m0/s1

InChI key

JCBPETKZIGVZRE-BYPYZUCNSA-N

Looking for similar products? Visit Product Comparison Guide

Application

(S)-(+)-2-Amino-1-butanol is a chiral amino alcohol that may be used in the synthesis of (S)-2-(6-benzylamino-9-isopropyl-9H-purin-2-ylamino) butan-1-ol, an (S)-enantiomer of roscovitine. It can also be used to synthesize homochiral 2-methylpyrroles. (S)-(+)-2-Amino-1-butanol is an intermediate for the synthesis of (S,S)-ethambutol, an antibacterial agent for treating tuberculosis.

pictograms

Corrosion
GHS05

signalword

Danger

hcodes

H314

Hazard Classifications

Skin Corr. 1B

Storage Class

8A - Combustible corrosive hazardous materials

wgk_germany

WGK 3

flash_point_f

203.0 °F - closed cup

flash_point_c

95 °C - closed cup

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Synthesis and configuration of the cyclin-dependent kinase inhibitor roscovitine and its enantiomer.
Wang S, et al
Tetrahedron Asymmetry, 12(20), 2891-2894 (2001)
Synthesis and photooxygenation of homochiral 2-methylpyrrole derivatives of chiral amino alcohols: simple, selective access to chiral bicyclic lactams
Aydogan F and Demir AS
Tetrahedron Asymmetry, 15(2), 259-265 (2004)
Enantioselective synthesis of (S, S)-ethambutol using proline-catalyzed asymmetric a-aminooxylation and a-amination
Kotkar SP and Sudalai A
Tetrahedron Asymmetry, 17(11), 1738-1742 (2006)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service