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109908

Sigma-Aldrich

Diethylene glycol methyl ether

99%

Synonym(s):

2-(2-Methoxyethoxy)ethanol, Methyldiglycol

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About This Item

Linear Formula:
CH3OCH2CH2OCH2CH2OH
CAS Number:
111-77-3
Molecular Weight:
120.15
Beilstein/REAXYS Number:
1697812
EC Number:
203-906-6
MDL number:
MFCD00002871
UNSPSC Code:
12352103
PubChem Substance ID:
329749265

vapor density

4.14 (vs air)

vapor pressure

0.2 mmHg ( 20 °C)

assay

99%

autoignition temp.

221 °C

expl. lim.

1.38-22.7 %

refractive index

n20/D 1.426 (lit.)

bp

194 °C (lit.)

mp

−70 °C (lit.)

density

1.023 g/mL at 25 °C (lit.)

SMILES string

COCCOCCO

InChI

1S/C5H12O3/c1-7-4-5-8-3-2-6/h6H,2-5H2,1H3

InChI key

SBASXUCJHJRPEV-UHFFFAOYSA-N

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pictograms

Health hazard
GHS08

signalword

Danger

hcodes

H360D

Hazard Classifications

Repr. 1B

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 1

flash_point_f

188.6 °F - closed cup

flash_point_c

87 °C - closed cup

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

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Certificates of Analysis (COA)

Lot/Batch Number
07316BW
12110AX
S31616
6830TR
6330TR

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B D Hardin et al.
Fundamental and applied toxicology : official journal of the Society of Toxicology, 6(3), 430-439 (1986-04-01)
Diethylene glycol monomethyl ether (diEGME) was one of 15 glycols tested in CD-1 mice using a short-term in vivo reproductive toxicity assay (Chernoff/Kavlock test). Because results were strongly suggestive of potential reproductive toxicity, a teratology study was conducted in Sprague-Dawley
R R Miller et al.
Fundamental and applied toxicology : official journal of the Society of Toxicology, 5(6 Pt 1), 1174-1179 (1985-12-01)
Male and female Fischer 344 rats were exposed to 0, 30, 100, or 216 ppm diethylene glycol monomethyl ether (DEGME) vapors (0, 0.15, 0.49, or 1.06 mg/liter) 6 hr/day, 5 days/week, for 13 weeks. The 216-ppm exposure level was the
Hao Zhu et al.
Chemical communications (Cambridge, England), 48(96), 11766-11768 (2012-11-02)
Rlyso, a highly selective and sensitive pH sensor, can stain lysosomes with a novel lysosome-locating group, methylcarbitol. Rlyso was successfully used to detect lysosomal pH changes during apoptosis or induced by chloroquine while avoiding the "alkalizing effect" on lysosomes of
T Kawamoto et al.
Toxicology, 62(3), 265-274 (1990-06-01)
Glycol ethers have been extensively used in industry over the past 40-50 years. Numerous studies on the toxicity of glycol ethers have been performed, however, the effects of glycol ethers on the hepatic drug metabolizing enzymes are still unknown. We
E Chapoteau et al.
Clinical chemistry, 38(9), 1654-1657 (1992-09-01)
We report a colorimetric method for determining lithium in blood serum without sample pretreatment or solvent-extraction steps. The method is based on a novel chromogenic ionophore that exhibits exceptionally high selectivity (much greater than 4000:1) for lithium over sodium. The
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