TCEB2
transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)
Synonyms:
ELOB, SIII
Species:
Human TCEB2 (6923), Mouse Tceb2 (67673), Rat Tceb2 (81807), Goat TCEB2 (100861051), domestic guinea pig Tceb2 (100713146), Zebrafish tceb2 (192341), cow TCEB2 (617277), domestic cat TCEB2 (100628310), dog TCEB2 (479873)
UniProtKB ID:
Gene ID:
- Human(6923) Summary: This gene encodes the protein elongin B, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. Pseudogenes have been identified on chromosomes 11 and 13. [provided by RefSeq, Aug 2008]
- Mouse(67673) transcription elongation factor B (SIII), polypeptide 2
- Rat(81807) transcription elongation factor B (SIII), polypeptide 2
- Goat(100861051) transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)
- domestic guinea pig(100713146) transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)
- Zebrafish(192341) transcription elongation factor B (SIII), polypeptide 2 (18kD, elongin B)
- cow(617277) transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)
- domestic cat(100628310) transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)
- dog(479873) transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-TCEB2 antibody produced in mouse, clone 2B4, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
KD-Validated Anti TCEB2 Antibody, clone 23GB5610, Rabbit Monoclonal, clone 23GB5610, recombinant rabbit monoclonal, expressed in HEK293 cells,
Species Reactivity
human, rat
Application
flow cytometry
western blot
western blot
KD-Validated Anti TCEB2 Antibody, clone 23GB5615, Rabbit Monoclonal, clone 23GB5615, recombinant rabbit monoclonal, expressed in HEK293 cells,
Species Reactivity
human
Application
flow cytometry
western blot
western blot