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SPTBN4

spectrin, beta, non-erythrocytic 4

Synonyms:
QV, SPNB4, SPTBN3
Species:
UniProtKB ID:
Gene ID:
  • Human(57731) Summary: Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is composed of two antiparallel dimers of alpha- and beta- subunits. This gene is one member of a family of beta-spectrin genes. The encoded protein localizes to the nuclear matrix, PML nuclear bodies, and cytoplasmic vesicles. A highly similar gene in the mouse is required for localization of specific membrane proteins in polarized regions of neurons. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(80297) spectrin beta, non-erythrocytic 4
  • Rat(308458) spectrin, beta, non-erythrocytic 4
  • domestic guinea pig(100724245) spectrin, beta, non-erythrocytic 4
  • naked mole-rat(101697752) spectrin, beta, non-erythrocytic 4
  • domestic cat(101088707) spectrin, beta, non-erythrocytic 4
  • cow(537578) spectrin, beta, non-erythrocytic 4
  • sheep(101120011) spectrin, beta, non-erythrocytic 4
  • chicken(430775) spectrin, beta, non-erythrocytic 4
  • dog(484499) spectrin, beta, non-erythrocytic 4

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

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  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-beta 4 Spectrin-Atto 488 antibody produced in mouse, clone S393-2,
Species Reactivity
african green monkey, human
Application
immunofluorescence
western blot
Monoclonal Anti-beta 4 Spectrin-Atto 390 antibody produced in mouse, clone S393-2,
Species Reactivity
african green monkey, human
Application
immunofluorescence
western blot
Monoclonal Anti-beta 4 Spectrin-Atto 594 antibody produced in mouse, clone S393-2,
Species Reactivity
african green monkey, human
Application
immunofluorescence
western blot
Monoclonal Anti-beta 4 Spectrin-FITC antibody produced in mouse, clone S393-2,
Species Reactivity
african green monkey, human
Application
immunofluorescence
western blot
Monoclonal Anti-beta 4 Spectrin-Allophycocyanin antibody produced in mouse, clone S393-2,
Species Reactivity
african green monkey, human
Application
immunofluorescence
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Sptbn4,
Species
mouse