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HTR3E

5-hydroxytryptamine (serotonin) receptor 3E, ionotropic

Synonyms:
5-HT3-E, 5-HT3E, 5-HT3c1
Species:
Human HTR3E (285242), cow HTR3E (616094), dog HTR3E (488102), sheep HTR3E (101122747), domestic cat HTR3E (101089387), Horse HTR3E (100066981), naked mole-rat Htr3e (101717686)
UniProtKB ID:
A5X5Y0, A8IKD7, E9PGF1, Q495G1, Q495G3, Q6V706, Q6V707, Q7Z6B2
Gene ID:
  • Human(285242) Summary: This locus encodes a 5-hydroxytryptamine (serotonin) receptor subunit. The encoded protein, subunit E, may play a role in neurotransmission in myenteric neurons. Genes encoding subunits C, D and E form a cluster on chromosome 3. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Feb 2012]
  • cow(616094) 5-hydroxytryptamine (serotonin) receptor 3E, ionotropic
  • dog(488102) 5-hydroxytryptamine (serotonin) receptor 3E, ionotropic
  • sheep(101122747) 5-hydroxytryptamine (serotonin) receptor 3E, ionotropic
  • domestic cat(101089387) 5-hydroxytryptamine (serotonin) receptor 3E, ionotropic
  • Horse(100066981) 5-hydroxytryptamine (serotonin) receptor 3E, ionotropic
  • naked mole-rat(101717686) 5-hydroxytryptamine (serotonin) receptor 3E, ionotropic

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Small Molecule - Agonist

Product Number
Description
Species
S1688
SR 57227A, solid,
Species
human
M0763
Metoclopramide hydrochloride, solid,
Species
human
T104
Tropisetron monohydrochloride, solid, ≥98% (HPLC),
Species
rat, human
F112
(+)-Fenfluramine hydrochloride, ,
Species
human
Q1004
Quipazine maleate salt, ,
Species
human

Small Molecule - Allosteric Modulator

Product Number
Description
Species
D9190
DCEBIO, ≥98% (HPLC), solid,
Species
human

Small Molecule - Antagonist

Product Number
Description
Species
M0763
Metoclopramide hydrochloride, solid,
Species
human
T104
Tropisetron monohydrochloride, solid, ≥98% (HPLC),
Species
rat, human
A0590000
Amisulpride, European Pharmacopoeia (EP) Reference Standard,
Species
human
A2729
Amisulpride, ≥98% (HPLC),
Species
human
BP1090
Amisulpride, British Pharmacopoeia (BP) Reference Standard,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
HPA049764
Anti-HTR3E antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry

Small Molecule - Blocker

Product Number
Description
Species
T3146
Trimipramine maleate salt, ≥98% (TLC), powder,
Species
human
Z101
Zimelidine dihydrochloride, solid,
Species
human

Small Molecule - Inhibitor

Product Number
Description
Species
F1553
S-(+)-Fluoxetine hydrochloride, ≥98% (HPLC), solid,
Species
human
F1678
R-(−)-Fluoxetine hydrochloride, >98% (HPLC), solid,
Species
human
F2802
Fluvoxamine maleate, solid,
Species
human
S6319
Sertraline hydrochloride, ≥98% (HPLC),
Species
human
C7861
Citalopram hydrobromide, ≥98% (HPLC),
Species
human

Small Molecule - Ligand

Product Number
Description
Species
M1514
Nω-Methyl-5-hydroxy­trypt­amine oxalate salt, ≥90% (HPLC),
Species
human

Small Molecule - Metabolite

Product Number
Description
Species
H8876
5-Hydroxyindole-3-acetic acid, ≥98% (HPLC), crystalline,
Species
human

Small Molecule - Precursor

Product Number
Description
Species
H9772
5-Hydroxy-L-tryptophan, powder,
Species
human

esiRNA

Product Number
Description
Species
EHU010061
MISSION® esiRNA, targeting human HTR3E,
Species
human