GMNN
geminin, DNA replication inhibitor
Synonyms:
Gem
Species:
Human GMNN (51053), Mouse Gmnn (57441), Rat Gmnn (291137), sheep GMNN (101117456), Goat GMNN (100860987), domestic guinea pig Gmnn (100735738), Zebrafish gmnn (368320), dog GMNN (478739), domestic cat GMNN (101097559), naked mole-rat Gmnn (101719826) ...More
UniProtKB ID:
Gene ID:
- Human(51053) Summary: This gene encodes a protein that plays a critical role in cell cycle regulation. The encoded protein inhibits DNA replication by binding to DNA replication factor Cdt1, preventing the incorporation of minichromosome maintenance proteins into the pre-replication complex. The encoded protein is expressed during the S and G2 phases of the cell cycle and is degraded by the anaphase-promoting complex during the metaphase-anaphase transition. Increased expression of this gene may play a role in several malignancies including colon, rectal and breast cancer. Alternatively spliced transcript variants have been observed for this gene, and two pseudogenes of this gene are located on the short arm of chromosome 16. [provided by RefSeq, Oct 2011]
- Mouse(57441) geminin
- Rat(291137) geminin
- sheep(101117456) geminin, DNA replication inhibitor
- Goat(100860987) geminin, DNA replication inhibitor
- domestic guinea pig(100735738) geminin, DNA replication inhibitor
- Zebrafish(368320) geminin, DNA replication inhibitor
- dog(478739) geminin, DNA replication inhibitor
- domestic cat(101097559) geminin, DNA replication inhibitor
- naked mole-rat(101719826) geminin, DNA replication inhibitor
- cow(526377) geminin, DNA replication inhibitor
- chicken(421004) geminin, DNA replication inhibitor
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Geminin Antibody, clone 4B10.1, clone 4B10.1, from mouse,
Species Reactivity
human
Application
immunocytochemistry
western blot
western blot
Anti-GMNN antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-Geminin Antibody, clone 1K11 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human
Application
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Anti-GMNN antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence