ACVR1
activin A receptor, type I
Synonyms:
ACTRI, ACVR1A, ACVRLK2, ALK2, FOP, SKR1, TSRI
Species:
Human ACVR1 (90), Mouse Acvr1 (11477), Rat Acvr1 (79558), domestic guinea pig Acvr1 (100724428), naked mole-rat Acvr1 (101711343), chicken ACVR1 (395246), dog ACVR1 (478757), domestic cat ACVR1 (101091298), Horse ACVR1 (100050899), cow ACVR1 (338068)
UniProtKB ID:
Gene ID:
- Human(90) Summary: Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. This gene encodes activin A type I receptor which signals a particular transcriptional response in concert with activin type II receptors. Mutations in this gene are associated with fibrodysplasia ossificans progressive. [provided by RefSeq, Jul 2008]
- Mouse(11477) activin A receptor, type 1
- Rat(79558) activin A receptor, type I
- domestic guinea pig(100724428) activin A receptor, type I
- naked mole-rat(101711343) activin A receptor, type I
- chicken(395246) activin A receptor, type I
- dog(478757) activin A receptor, type I
- domestic cat(101091298) activin A receptor, type I
- Horse(100050899) activin A receptor, type I
- cow(338068) activin A receptor, type I
- sheep(443161) activin A receptor, type I
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ELISA
Product Number
Description
Species
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-ACVR1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-ACVR1 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse
Application
ELISA
western blot
western blot
Anti-ACVR1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, goat, horse, human, mouse, pig, rabbit, rat
Application
western blot
ANTI-ACTIVIN RECEPTOR TYPE IA (ACVR1) (CENTER R147) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human, mouse
Application
immunohistochemistry
western blot
western blot
Anti-ACVR1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Proteins
Product Number
Description
Species