SMB00131

3,5-Di-caffeoylquinic acid

≥95% (LC/MS-ELSD)

• Synonym(s): 3,5-DCQA, 3,5-Dicaffeoylquinate, 3,5-Dicaffeoylquinic acid, 3,5-O-Dicaffeoylquinic acid, Isochlorogenic Acid A
• Empirical Formula (Hill Notation): C₂₅H₂₄O₁₂
• CAS Number: 2450-53-5
• Molecular Weight: 516.45
• MDL number: MFCD00951290
• UNSPSC Code: 12352205
• PubChem Substance ID: 329824809
• NACRES: NA.25

Properties

• Quality Level: 200
• Assay: ≥95% (LC/MS-ELSD)
• form: solid
• application(s): metabolomics; vitamins, nutraceuticals, and natural products
• storage temp.: −20°C
• SMILES string: O[C@H]1[C@@H](C[C@@](O)(C[C@H]1OC(=O)\C=C\c2ccc(O)c(O)c2)C(O)=O)OC(=O)\C=C\c3ccc(O)c(O)c3
• InChI: 1S/C25H24O12/c26-15-5-1-13(9-17(15)28)3-7-21(30)36-19-11-25(35,24(33)34)12-20(23(19)32)37-22(31)8-4-14-2-6-16(27)18(29)10-14/h1-10,19-20,23,26-29,32,35H,11-12H2,(H,33,34)/b7-3+,8-4+/t19-,20-,23-,25+/m1/s1
• InChI key: KRZBCHWVBQOTNZ-PSEXTPKNSA-N

Description

General description

3,5-Dicaffeoylquinic acid is a phenolic acid found in the flower buds of Lonicera japonica Thunb. It has been used in pharmacologic, as well as food, and cosmetic research.

Application

3,5-Di-caffeoylquinic acid has been used as a reference standard for quantification of the phenolic compound of Artemisia species using high-performance liquid chromatography with diode array detection (HPLC-DAD). It has also been used as a reference standard to quantify the polyphenolic compounds found in Helianthus tuberosus L. (Jerusalem artichoke) using high-performance liquid chromatography-ultraviolet (HPLC-UV) technique.

Biochem/physiol Actions

3,5-Di-caffeoylquinic acid exerts neuroprotective effects against in vitro retinal damage mediated by its antioxidant properties. It is a potent maltase inhibitor.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable