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SAB4503057

Sigma-Aldrich

Anti-PGP9.5 antibody produced in rabbit

affinity isolated antibody

Synonym(s):

UCH-L1, neuron cytoplasmic protein 9.5, ubiquitin carboxyl-terminal hydrolase isozyme L1, ubiquitin thiolesterase L1

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 24 kDa

species reactivity

mouse, rat, human

concentration

~1 mg/mL

technique(s)

ELISA: 1:5000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... UCHL1(7345)

General description

Anti-PGP9.5 Antibody detects endogenous levels of total PGP9.5 protein.
The PGP9.5 (protein gene product 9.5) gene is mapped to human chromosome 4p13. The encoded protein is predominantly expressed in the brain.

Immunogen

The antiserum was produced against synthesized peptide derived from human PGP9.5.

Immunogen Range: 171-220

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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Rie B Hansen et al.
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Pain is a common complication for patients with metastatic bone disease. Animal models suggest that the pain, in part, is driven by pathological sprouting and reorganization of the nerve fibers innervating the bone. Here, we investigate how these findings translate
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Materials today. Bio, 26, 101075-101075 (2024-05-13)
Regenerating skin nerves in deep burn wounds poses a significant clinical challenge. In this study, we designed an electrospun wound dressing called CuCS/Cur, which incorporates copper-doped calcium silicate (CuCS) and curcumin (Cur). The unique wound dressing releases a bioactive Cu2+-Cur
Dayu Pan et al.
eLife, 12 (2024-06-19)
Spinal pain affects individuals of all ages and is the most common musculoskeletal problem globally. Its clinical management remains a challenge as the underlying mechanisms leading to it are still unclear. Here, we report that significantly increased numbers of senescent
Shingo Ishihara et al.
Arthritis research & therapy, 23(1), 103-103 (2021-04-09)
C-C chemokine receptor 2 (CCR2) signaling plays a key role in pain associated with experimental murine osteoarthritis (OA) after destabilization of the medial meniscus (DMM). Here, we aimed to assess if CCR2 expressed by intra-articular sensory neurons contributes to knee
A Nakasone et al.
Osteoarthritis and cartilage, 30(8), 1130-1139 (2022-05-16)
Focal lesions within the subchondral bone, termed subchondral bone cysts (SBCs), are clinically accepted radiographic markers of advanced osteoarthritis (OA), but their etiology in the hip is not well understood. This study used micro-computed tomography (μCT), and histological and immunocytological

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