S2500

Scopoletin

≥99%

• Synonym(s): 6-Methoxyumbelliferone, 6-Methylesculetin, 7-Hydroxy-6-methoxy-2H-1-benzopyran-2-one, 7-Hydroxy-6-methoxycoumarin, Buxuletin, Chrysatropic acid, Escopoletin, Esculetin-6-methyl ether, Gelseminic acid, Murrayetin
• Empirical Formula (Hill Notation): C₁₀H₈O₄
• CAS Number: 92-61-5
• Molecular Weight: 192.17
• Beilstein: 156296
• EC Number: 202-171-9
• MDL number: MFCD00006872
• UNSPSC Code: 12171501
• PubChem Substance ID: 24899524
• NACRES: NA.28

Properties

• Assay: ≥99%
• mp: 203-205 °C (lit.)
• SMILES string: COc1cc2C=CC(=O)Oc2cc1O
• InChI: 1S/C10H8O4/c1-13-9-4-6-2-3-10(12)14-8(6)5-7(9)11/h2-5,11H,1H3
• InChI key: RODXRVNMMDRFIK-UHFFFAOYSA-N
• Gene Information: human ... ACHE(43)

Description

Application

• Production of Polyphenolic Natural Products by Bract-Derived Tissue Cultures of Three Medicinal Tilia spp.: A Comparative Untargeted Metabolomics Study.: This study investigates the production of polyphenolic compounds, including scopoletin, in tissue cultures derived from the bracts of three medicinal Tilia species. The research highlights the potential of these cultures in producing valuable natural products (Szűcs et al., 2024).

Biochem/physiol Actions

Dye that can be used to detect the release of reactive oxygen species during the oxidative burst; peroxynitrite scavenger; acetylcholinesterase inhibitor.

Scopoletin significantly increases activity of lipoprotein lipase in adipocytes by promoting transcription of the LPL gene. It also partially reverses inhibition of LPL by TNF-α.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves