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P8925

Sigma-Aldrich

Octaethylene glycol monododecyl ether

≥98% (GC)

Synonym(s):

C12E8, Dodecyl octaethylene glycol ether, Dodecyloctaglycol, Polyoxyethylene (8) lauryl ether

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About This Item

Linear Formula:
CH3(CH2)11(OCH2CH2)8OH
CAS Number:
3055-98-9
Molecular Weight:
538.75
Beilstein:
1893466
MDL number:
MFCD00043234
UNSPSC Code:
12161900
PubChem Substance ID:
24898996
NACRES:
NA.25

description

non-ionic

Quality Level

100

Assay

≥98% (GC)

form

solid

mol wt

average mol wt 66,000

aggregation number

123

CMC

0.11

SMILES string

CCCCCCCCCCCCOCCOCCOCCOCCOCCOCCOCCOCCO

InChI

1S/C28H58O9/c1-2-3-4-5-6-7-8-9-10-11-13-30-15-17-32-19-21-34-23-25-36-27-28-37-26-24-35-22-20-33-18-16-31-14-12-29/h29H,2-28H2,1H3

InChI key

YYELLDKEOUKVIQ-UHFFFAOYSA-N

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General description

Octaethylene glycol monododecyl ether is a nonionic detergent.

Application

Octaethylene glycol monododecyl ether has been used in a study to assess intestinal sodium transport mechanisms. It has also been used in a study to investigate interactions between dyes and surfactants in inkjet ink used for textiles.
Detergent used for the study of membrane proteins in a native-like state, e.g. ATPase. Used in a mixed micellar assay for lipoxygenase acting at neutral pH and for functional reconstitution of influenza virus envelopes.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Cleyton C Domingues et al.
The Journal of membrane biology, 234(3), 195-205 (2010-03-27)
Transient lateral microdomains or lipid rafts play important roles in many physiological membrane-mediated cell processes. Detergent-resistant membranes (DRMs) are good models for the study of lipid rafts. Here we report that DRMs can be obtained by treating human erythrocytes with
Ju-Young Park et al.
Journal of oleo science, 60(12), 627-637 (2011-11-30)
Optimal preparation of inkjet ink should be possible through the elucidation of the relationship between dye/additive interactions and ink performance. In the present study, the interactions between the dyes and surfactant additives were investigated. To investigate the physical properties of
M R Wenk et al.
Biophysical journal, 72(4), 1719-1731 (1997-04-01)
The interaction of the nonionic detergent octyl-beta-D-glucopyranoside (OG) with lipid bilayers was studied with high-sensitivity isothermal titration calorimetry (ITC) and solid-state 2H-NMR spectroscopy. The transfer of OG from the aqueous phase to lipid bilayers composed of 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) can be
G C Troiano et al.
Biophysical journal, 75(2), 880-888 (1998-07-24)
The effects of a nonionic surfactant, octaethyleneglycol mono n-dodecyl ether (C12E8), on the electroporation of planar bilayer lipid membranes made of the synthetic lipid 1-pamitoyl 2-oleoyl phosphatidylcholine (POPC), was studied. High-amplitude ( approximately 100-450 mV) rectangular voltage pulses were used
Cédric Montigny et al.
Biochemical and biophysical research communications, 391(1), 1067-1069 (2009-12-17)
Many membrane proteins become labile when they are solubilized by detergent. Here we show that the presence of high concentrations of glycyl betaine stabilizes one of these proteins, the sarcoplasmic reticulum Ca(2+)-ATPase (SERCA1a), solubilized with nonionic detergents like n-dodecyl beta-d-maltopyranoside
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