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Key Documents

D6511

Sigma-Aldrich

2,6-Dichloroquinone-4-chloroimide

≥95% (TLC), suitable for detection of phenols

Synonym(s):

N,2,6-Trichloro-p-benzoquinoneimide, Gibb’s reagent

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About This Item

Empirical Formula (Hill Notation):
C6H2Cl3NO
CAS Number:
Molecular Weight:
210.45
Beilstein:
2364249
EC Number:
MDL number:
UNSPSC Code:
12171500
PubChem Substance ID:
NACRES:
NA.47

Quality Level

Assay

≥95% (TLC)

form

powder or crystals

mp

65-67 °C (lit.)

solubility

ethanol: soluble 50 mg/mL, clear, yellow

suitability

suitable for detection of phenols

storage temp.

2-8°C

SMILES string

Cl\N=C1\C=C(Cl)C(=O)C(Cl)=C1

InChI

1S/C6H2Cl3NO/c7-4-1-3(10-9)2-5(8)6(4)11/h1-2H

InChI key

YHUMTHWQGWPJOQ-UHFFFAOYSA-N

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Pictograms

FlameExclamation mark

Signal Word

Danger

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Self-react. C - Skin Irrit. 2

Storage Class Code

4.1A - Other explosive hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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N A El-Ragehy et al.
Journal of pharmaceutical and biomedical analysis, 29(1-2), 121-137 (2002-06-14)
Six procedures have been suggested for the determination of the antihistaminic agent, mequitazine, in the presence of its degradate. Mequitazine, having a phenothiazine group, undergoes peroxide oxidation and the corresponding sulphone is produced. Its identity was confirmed by IR and
I L Tsai et al.
Planta medica, 66(5), 403-407 (2000-07-26)
Four new cytotoxic neolignans, machilusol A (1), machilusol C (3), machilusol D (4), machilusol E (5) as well as two new inactive neolignans, machilusol B (2) and machilusol F (6), were isolated from the stem wood of Machilus obovatifolia. All
Use of 2,6-dichloroquinone chlorimide for the spectrophotometric determination of halogenated derivatives of 8-hydroxyquinoline.
F Belal
The Analyst, 109(5), 615-618 (1984-05-01)
A G Kobylianskiĭ et al.
Voprosy meditsinskoi khimii, 40(4), 40-46 (1994-07-01)
Quantitative estimation of phenol content in human urine involving Gibbs reagent was described in detail; the procedure was applied for screening test of people. The Gibbs reagent was synthesized from commonly available substances 2,6-dibromine-4-aminophenol and 4-nitrophenol. Estimation of total and
G G Mohamed et al.
Journal of pharmaceutical and biomedical analysis, 28(6), 1127-1133 (2002-06-07)
A simple, rapid and sensitive spectrophotometric method for the determination of sulbutamol in pure form and in different pharmaceutical preparations has been developed. The charge transfer (CT) reaction between salbutamol as electron donor and 2,6-dichloroquinone chlorimide (DCQ) and 7,7,8,8-tetracyanoquinodimethane (TCNQ)

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