Section 3 of SDS shows only the hazardous component information. Product# A5955 contains microgram amounts of Amphotericin B. At this concentration it is non-hazardous, hence section 3 of SDS does not list Amphotericin B.
A5955
Antibiotic Antimycotic Solution (100×), Stabilized
suspension, suitable for cell culture, BioReagent
Synonym(s):
Penicillin-Streptomycin-Amphotericin B Suspension
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Product Name
Antibiotic Antimycotic Solution (100×), Stabilized, with 10,000 units penicillin, 10 mg streptomycin and 25 μg amphotericin B per mL, 0.1 μm filtered, BioReagent, suitable for cell culture
Quality Level
sterility
0.1 μm filtered
product line
BioReagent
form
suspension
technique(s)
cell culture | mammalian: suitable
impurities
endotoxin, tested
color
yellow
antibiotic activity spectrum
Gram-negative bacteria
Gram-positive bacteria
fungi
yeast
application(s)
agriculture
Mode of action
cell wall synthesis | interferes
shipped in
dry ice
storage temp.
−20°C
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General description
Antibiotic Antimycotic Solution is formulated to contain 10,000 units penicillin, 10 mg streptomycin and 25μg Amphotericin B per mL, and is solubilized in a proprietary citrate buffer. It is recommended for use in cell culture applications at 10mL/L. Antibioticantimycotic solution is generally used to prevent the growth of harmful microorganisms including bacteria and fungi in cell culture media.[1]
Application
Antibiotic antimycotic solution has been used:
- as a supplement in different types of cell culture media.[2][3][4]
- as a component of phosphate buffer saline (PBS) sterile solution to prevent contamination of periodontal ligament fibroblasts (PDLF) tissues that are isolated and cultured in the experiments.[5]
- as a component of storage solution for preserving tracheal segments harvested for subsequent experimental investigation.[6]
Biochem/physiol Actions
Mode of Action: Penicillin acts by inhibiting bacterial cell-wall synthesis. Streptomycin inhibits prokaryote protein synthesis by preventing the transition from initiation complex to chain-elongating ribosome and causes miscoding. Amphotericin B interferes with fungal membrane permeability by forming channels in the membranes and causing small molecules to leak out.
Antimicrobial spectrum: Includes Gram-negative bacteria, Gram-positive bacteria, fungi and yeasts.
Antimicrobial spectrum: Includes Gram-negative bacteria, Gram-positive bacteria, fungi and yeasts.
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Product No.
Description
Pricing
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Skin Sens. 1
Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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I am looking at the SDS for product number A5955, Antibiotic Antimycotic soln. I do not see Amphotericin B in composition of ingredients (3.2 mixtures). I want to know why. Thank you.
1 answer-
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