85580
Spermidine trihydrochloride
≥99.0% (AT)
Synonym(s):
N-(3-Aminopropyl)-1,4-butanediamine trihydrochloride
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About This Item
Linear Formula:
NH2(CH2)3NH(CH2)4NH2 · 3HCl
CAS Number:
Molecular Weight:
254.63
Beilstein:
3552356
EC Number:
MDL number:
UNSPSC Code:
12352204
PubChem Substance ID:
NACRES:
NA.77
Recommended Products
biological source
microbial
synthetic
Quality Level
Assay
≥99.0% (AT)
form
powder
mp
~250 °C (dec.)
257-259 °C (lit.)
solubility
H2O: 0.1 g/mL, clear, colorless
storage temp.
room temp
SMILES string
Cl[H].Cl[H].Cl[H].NCCCCNCCCN
InChI
1S/C7H19N3.3ClH/c8-4-1-2-6-10-7-3-5-9;;;/h10H,1-9H2;3*1H
InChI key
LCNBIHVSOPXFMR-UHFFFAOYSA-N
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General description
Spermidine is a polyamine and a trivalent organic cation.
Application
Spermidine trihydrochloride has been used as standard for the detection of biogenic amines using HPLC.
Biochem/physiol Actions
Inhibits neuronal nitric oxide synthase (nNOS). Binds and precipitates DNA; Stimulates T4 polynucleotide kinase activity.
Inhibits neuronal nitric oxide synthase (nNOS). Binds and precipitates DNA; may be used for purification of DNA binding proteins. Stimulates T4 polynucleotide kinase activity.
Spermidine modulates various cellular activities like cellular development and differentiation, stability of DNA and apoptosis.
Caution
Solutions should be sterile-filtered, not autoclaved, if sterile solution is necessary. Spermidine deaminates with time; solutions should be stored frozen. Prepare new solutions frequently.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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