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40232

Sigma-Aldrich

N-Dodecyl-N,N-dimethyl-3-ammonio-1-propanesulfonate

≥97.0% (dried material, CHN)

Synonym(s):

3-(N,N-Dimethyldodecylammonio)propanesulfonate, 3-(N,N-Dimethyllaurylammonio)propanesulfonate, 3-(Dodecyldimethylammonio)propanesulfonate, 3-(Lauryldimethylammonio)propanesulfonate, Dodecyldimethyl(3-sulfopropyl)ammonium hydroxide inner salt, Lauryl sulfobetaine, SB3-12

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About This Item

Linear Formula:
CH3(CH2)11N+(CH3)2CH2CH2CH2SO3-
CAS Number:
14933-08-5
Molecular Weight:
335.55
Beilstein:
4145308
EC Number:
239-002-3
MDL number:
MFCD00036909
UNSPSC Code:
12161900
eCl@ss:
32190102
PubChem Substance ID:
57649944
NACRES:
NA.25

description

zwitterionic

Quality Level

200

Assay

≥97.0% (dried material, CHN)

form

powder

mol wt

micellar avg mol wt 18,500

aggregation number

55

ign. residue

≤0.1%

loss

≤1% loss on drying, 110 °C

CMC

2-4 mM (20-25°C)

cation traces

Ca: ≤20 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤50 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Na: ≤150 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤5 mg/kg

application(s)

detection

SMILES string

CCCCCCCCCCCC[N+](C)(C)CCCS([O-])(=O)=O

InChI

1S/C17H37NO3S/c1-4-5-6-7-8-9-10-11-12-13-15-18(2,3)16-14-17-22(19,20)21/h4-17H2,1-3H3

InChI key

IZWSFJTYBVKZNK-UHFFFAOYSA-N

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General description

N-Dodecyl-N,N-dimethyl-3-ammonio-1-propanesulfonate is a zwitterionic detergent that is used for protein solubilization.

Application

N-Dodecyl-N,N-dimethyl-3-ammonio-1-propanesulfonate has been used as a component of trypsin buffer for the dialysis of protein solution.

Other Notes

Zwitterionic surfactant which effectively solubilizes cardiac 5′-nucleotidase

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

230.0 °F - closed cup

Flash Point(C)

110 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Masahiro Yoshizawa-Fujita et al.
The journal of physical chemistry. B, 114(49), 16373-16380 (2010-11-23)
We describe zwitterion, 3-(1-butyl-1H-imidazol-3-ium-3-yl)propane-1-sulfonate (Bimps), mixtures with 1,1,1-trifluoro-N-(trifluoromethylsulfonyl)methanesulfoneamide (HN(Tf)(2)) as new proton transport electrolytes. We report proton transport mechanisms in the mixtures based on results from several methods including thermal analyses, the complex-impedance method, and the pulsed field gradient spin
E H Chowdhury et al.
Journal of biotechnology, 119(4), 343-347 (2005-08-13)
Purification of plasmid DNA from bacteria is an essential tool in recombinant DNA technology and has become an essential task in laboratories to industries. Moreover, the recent progress of "Gene therapy" and "Genetic vaccination" also demands production of pharmaceutical grade
Suguru Yamamoto et al.
Biochemistry, 43(34), 11075-11082 (2004-08-25)
In beta(2)-microglobulin-related (Abeta2M) amyloidosis, partial unfolding of beta(2)-microglobulin (beta2-m) is believed to be prerequisite to its assembly into Abeta2M amyloid fibrils in vivo. Although low pH or 2,2,2-trifluoroethanol at a low concentration has been reported to induce partial unfolding of
Hongying Jia et al.
Journal of chromatography. A, 1143(1-2), 88-97 (2007-02-03)
With the accelerating development of new drugs, there is a high need for rapid and simple screening technologies. In this paper, a new in vitro method, dodecyl dimethyl betaine (BS-12) micellar liquid chromatography (MLC) was presented for prediction of protein-drug
D Boehning et al.
The EMBO journal, 19(20), 5450-5459 (2000-10-18)
Inositol 1,4,5-trisphosphate receptors (IP(3)Rs) are a family of intracellular Ca(2+) channels that exist as homo- or heterotetramers. In order to determine whether the N-terminal ligand-binding domain is in close physical proximity to the C-terminal pore domain, we prepared microsomal membranes
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