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02286

Sigma-Aldrich

Kollidon® 25

Synonym(s):

Polyvinylpyrrolidone, PVP, Polyvidone, Povidone

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About This Item

Linear Formula:
(C6H9NO)n
CAS Number:
9003-39-8
MDL number:
MFCD00149016
UNSPSC Code:
12162002
NACRES:
NA.25
Pricing and availability is not currently available.

Quality Level

200

impurities

≤1 ppm hydrazine
≤10 ppm heavy metals (verified on random samples only)
≤10 ppm lead (verified on random samples only)
≤10 ppm vinylpyrrolidinone
≤3.0% 2-pyrrolidone
≤400 ppm peroxides (as H2O2)
≤5.0% water
≤500 ppm aldehydes (as acetaldehyde)
≤5000 ppm formic acid
12.0-12.8% nitrogen (anhydrous basis)

ign. residue

≤0.1% (verified on random samples only)

pH

3.0-5.0

suitability

complies for Infrared spectrum

application(s)

sample preservation

SMILES string

C=CN1CCCC1=O
C=CN1CCCC1=O

InChI

1S/C6H9NO/c1-2-7-5-3-4-6(7)8/h2H,1,3-5H2

InChI key

WHNWPMSKXPGLAX-UHFFFAOYSA-N

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Application

The Kollidon products consist of soluble and insoluble grades of polyvinylpyrrolidone (PVP) of various molecular weights and particle sizes. It is used as dry binders, film-formers, stabilizers in suspensions, dispersants for pigments, enzyme stabilisiers and bioavailablility improvers.
Kollidon SR is a blend of polyvinyl acetate and povidone (K 30) in the ratio 8:2 for use as matrix-forming agent. This research grade product is intended for use in R&D and development only.

Other Notes

Polyvinylpyrrolidone is a component of Denhardt′s Solution and is included at a concentration of 1% (w/v) in the standard 50X stock solution.

Legal Information

Kollidon is a registered trademark of BASF SE

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
BCCK3379
BCCG4333
BCCD9628
BCCC8593
BCCC8592

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Yan-Yan Yin et al.
Inorganic chemistry, 51(8), 4784-4790 (2012-03-31)
Chiral Ni(II) coordination compounds with structures of [NiL(H(2)O)(3)] (1) and {[NiL(H(2)O)]·0.5H(2)O}(n) (2) (H(2)L = thiazolidine 2,4-dicaboxlic acid) have been successfully synthesized by the reaction of Ni(CH(3)COO)(2)·4H(2)O and H(2)L in aqueous solution at 25 and 80 °C, respectively. From the same
Jianxin Zhang et al.
International journal of pharmaceutics, 414(1-2), 210-217 (2011-06-02)
Nanothermal analysis (NTA) supported by atomic force microscopy imaging has been used to study the changes that occur at the surfaces of solid dispersions of the drug felodipine and the water soluble polymer, polyvinylpyrrolidone (PVP) on exposure to standard pharmaceutical
Camila Braga Dornelas et al.
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques, 14(1), 17-35 (2011-04-20)
This work describes the preparation of new nanocomposites based on lamellar silicates (AAM-alkyl ammonium montmorillonite) obtained by the intercalation of PVP K30 and glyceril monostearate. By XRD, TGA and DSC analysis the AAM was characterized and its compactation characteristics, functionality
Ajit S Narang et al.
Journal of pharmaceutical sciences, 101(1), 127-139 (2011-11-24)
Reactive peroxides in povidone often lead to degradation of oxidation-labile drugs. To reduce peroxide concentration in povidone, the roles of storage conditions, antioxidants, and silicates were investigated. Povidone alone and its physical mixtures with ascorbic acid, propyl gallate, sodium sulfite
Liyun Ren et al.
Nanoscale, 5(6), 2337-2345 (2013-02-09)
PLLA fibrous tissue scaffolds with controlled fiber nanoscale surface roughness are fabricated with a novel centrifugal jet spinning process. The centrifugal jet spinning technique is a highly efficient synthesis method for micron- to nano-sized fibers with a production rate up
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Questions

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  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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