RDD036
BICINE
Redi-Dri™, ≥99%, free-flowing
Synonym(s):
N,N-Bis(2-hydroxyethyl)glycine
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About This Item
Empirical Formula (Hill Notation):
C6H13NO4
CAS Number:
Molecular Weight:
163.17
Beilstein:
1769362
MDL number:
UNSPSC Code:
12161700
NACRES:
NA.21
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product line
Redi-Dri™
Quality Level
Assay
≥99%
quality
free-flowing
useful pH range
7.6-9.0
7.6-9.0
pKa (25 °C)
8.3
SMILES string
OCCN(CCO)CC(O)=O
InChI
1S/C6H13NO4/c8-3-1-7(2-4-9)5-6(10)11/h8-9H,1-5H2,(H,10,11)
InChI key
FSVCELGFZIQNCK-UHFFFAOYSA-N
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General description
Bicine is an inorganic compound used to make Bicine buffer, a "Good buffer" that is commonly used in molecular biology and biochemistry. Bicine is a zwitterionic substituted glycine that is stable and soluble in water. It is has a pKa of 8.3, ideal for biological sytems with a pH range of 7.6 - 9.0.
Application
Redi-Dri™ is an innovative packaging product line that helps eliminate clumping material by adding extra packaging process steps without any chemical additives, anti-clumping agents, or hydrophobic compounds. Redi Dri offers a more convenient and safer way to handle the products.
Bicine is typically used for protein analysis:
- for SDS-PAGE or Western blot assay, for column wash buffer, to pH solutions, to make digestion buffer for GFP & FRET Microscopy
- labeling buffer to prepare antibody solution for labeing for fluorecent assays
Recommended buffer for low temperature biochemical work. Used in the preparation of stable substrate solution for serum guanase determination. Spacer in plasma protein fractionation with Sephadex® by isotachophoresis.
Features and Benefits
- Redi-Dri™ design controls moisture for hygroscopic chemicals that commonly clump
- Anhydrous powder remains free-flowing and easy to use
- Eliminates clumps, for safer routine use in lab
- Maintains product moisture, quality, and attributes
Other Notes
For additional information on our range of Biochemicals, please complete this form.
Legal Information
Redi-Dri is a trademark of Sigma-Aldrich Co. LLC
Sephadex is a registered trademark of Cytiva
comparable product
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Find documentation for the products that you have recently purchased in the Document Library.
Imaging protein interactions by FRET microscopy: labeling proteins with fluorescent dyes
Verveer PJ et al.
CSH Protocols, 2006, pdb-pdb (2006)
Probing Protein Interactions Using GFP and FRET * Stage 1: Labeling Proteins with Fluorescent Dyes
Joseph Sambrook, David W Russell
CSH Protocols, 2006, pdb-pdb (2006)
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