32671
Carnidazole
VETRANAL®, analytical standard
Synonym(s):
[2-(2-Methyl-5-nitro-imidazol-1-yl)ethyl]thiocarbamic acid O-methyl ester
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About This Item
Empirical Formula (Hill Notation):
C8H12N4O3S
CAS Number:
Molecular Weight:
244.27
Beilstein:
620260
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24
Recommended Products
grade
analytical standard
Quality Level
product line
VETRANAL®
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
application(s)
forensics and toxicology
pharmaceutical (small molecule)
veterinary
format
neat
SMILES string
COC(=S)NCCn1c(C)ncc1[N+]([O-])=O
InChI
1S/C8H12N4O3S/c1-6-10-5-7(12(13)14)11(6)4-3-9-8(16)15-2/h5H,3-4H2,1-2H3,(H,9,16)
InChI key
OVEVHVURWWTPFC-UHFFFAOYSA-N
General description
Carnidazoles belong to the class of nitroimidazole compounds that are generally utilized for the treatment of various diseases in poultry, cattle and pigs.
Application
Carnidazole may be used as an analytical reference standard for the determination of the analyte in:
- Eggs by liquid chromatography-tandem mass spectrometry (LC-MS/MS).
- Environmental water samples by dispersive liquid-liquid microextraction (DLLME), followed by micellar electrokinetic chromatography (MEKC).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Recommended products
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
Legal Information
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Dam. 1 - Skin Sens. 1
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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P Chaudhuri et al.
European journal of obstetrics, gynecology, and reproductive biology, 10(5), 325-328 (1980-06-01)
A double-blind controlled clinical trial of the new, not yet commercially available drug, carnidazole and tinidazole, was carried out in 77 women with a proven vaginal trichomoniasis. 39 patients and their sexual partners received a single dose of 2 g
Novel cation selective exhaustive injection-sweeping procedure for 5-nitroimidazole determination in waters by micellar electrokinetic chromatography using dispersive liquid-liquid microextraction.
Hernandez-Mesa, et al.
Journal of Chromatography A, 1341(46), 65-72 (2014)
[Study of carnidazole (R 25831). A new therapeutic agent for vaginal trichomoniasis].
V Fonzé et al.
Revue medicale de Liege, 34(19), 811-815 (1979-10-01)
Development and validation of a rapid method for the determination and confirmation of 10 nitroimidazoles in animal plasma using liquid chromatography tandem mass spectrometry.
Cronly M, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 877(14-15), 1494-1500 (2009)
L Van Vaeck et al.
Biomedical & environmental mass spectrometry, 16(1-12), 121-129 (1988-10-01)
Laser microprobe mass analysis (LAMMA) was used for the structural characterization of polyfunctional drugs and their oxygenated metabolites, in particular the N-oxides. The spectra usually yield the molecular weight as well as intense fragments. The structural information is characteristically distributed
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