Skip to Content
Merck
All Photos(1)

Key Documents

MAB1912

Sigma-Aldrich

Anti-Procollagen Type I Antibody, NT, clone M-58

culture supernatant, clone M-58, Chemicon®

Synonym(s):

Anti-Procollagen Antibody, Clone M-58 Anti-Procollagen, Type I Procollagen Detection

Sign Into View Organizational & Contract Pricing


About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rat

Quality Level

antibody form

culture supernatant

clone

M-58, monoclonal

species reactivity

human

should not react with

rat, hamster, mouse

manufacturer/tradename

Chemicon®

technique(s)

immunohistochemistry: suitable (paraffin)

isotype

IgG2α

NCBI accession no.

UniProt accession no.

target post-translational modification

unmodified

Gene Information

human ... COL1A1(1277)

Specificity

Recognizes Human pro-collagen I. MAB1912 labels the amino-terminal pro-peptide.

Application

Detect Procollagen Type I using this Anti-Procollagen Type I Antibody, N-terminus, clone M-58 validated for use in IH(P).
Immunohistochemistry: 1:10,000-1:50,000 (fresh frozen tissue sections.)

Suitable for formaldehyde/formalin fixed paraffin sections, suggested starting dilution 1:100-1:1000, after treatment with 1% trypsin, 20 minutes at room temperature. Does not stain mature collagen fibers in tissue. Localized intracellularly in cells producing pro-collagen I. Not recommended for Western Blots Optimal working dilutions must be determined by end user.

Analysis Note

Control
Skin tissue

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

WGK

WGK 2


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

R E B Watson et al.
The British journal of dermatology, 161(2), 419-426 (2009-05-15)
Very few over-the-counter cosmetic 'anti-ageing' products have been subjected to a rigorous double-blind, vehicle-controlled trial of efficacy. Previously we have shown that application of a cosmetic 'anti-ageing' product to photoaged skin under occlusion for 12 days can stimulate the deposition
Are fibrocytes present in pediatric burn wounds?
Andrew J A Holland,Sarah L S Tarran,Heather J Medbury,Ann K Guiffre
Journal of Burn Care & Research : Official Publication of the American Burn Association null
John P McCook et al.
Clinical, cosmetic and investigational dermatology, 9, 167-174 (2016-08-16)
To examine the effect of sodium copper chlorophyllin complex on the expression of biomarkers of photoaged dermal extracellular matrix indicative of skin repair. Following a previously published 12-day clinical assessment model, skin biopsy samples from the forearms of four healthy
Platelet-rich fibrin versus albumin in surgical wound repair: a randomized trial with paired design.
Danielsen, Patricia L, et al.
Annals of Surgery, 251, 825-831 (2010)
Myofibroblast and endothelial cell proliferation during murine myocardial infarct repair.
Virag, JI; Murry, CE
The American Journal of Pathology null

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service