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Sigma-Aldrich

Cathepsin L Inhibitor III

The Cathepsin L Inhibitor III controls the biological activity of Cathepsin L. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

Synonym(s):

Cathepsin L Inhibitor III, Z-FY( t-Bu)-DMK, Z-FY(t-Bu)-DMK

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About This Item

Empirical Formula (Hill Notation):
C31H34N4O5
Molecular Weight:
542.63
UNSPSC Code:
12352200
NACRES:
NA.77

Quality Level

Assay

≥98% (TLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
protect from light

color

white to light yellow

solubility

DMSO: 5 mg/mL

shipped in

ambient

storage temp.

−20°C

General description

An irreversible inhibitor of Cathepsin L (Cat. No. 219402). About 10,000-fold more effective against cathepsin L than cathepsin S.
An irreversible inhibitor of Cathepsin L (Cat. No. 219402). About 10,000-fold more effective against cathepsin L than cathepsin S.

Biochem/physiol Actions

Cell permeable: yes
Primary Target
Cathepsin L
Product does not compete with ATP.
Reversible: no

Warning

Toxicity: Standard Handling (A)

Sequence

Z-Phe-Tyr(t-Bu)-diazomethylketone

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 weeks at -20°C.

Other Notes

Shaw, E., et al. 1993. FEBS Lett. 334, 340.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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