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Key Documents

17-211

Sigma-Aldrich

Acetyl-Histone H4 Antibody Set

Upstate®, from rabbit

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About This Item

UNSPSC Code:
12161503
eCl@ss:
32161000
NACRES:
NA.32

biological source

rabbit

Quality Level

species reactivity

Saccharomyces cerevisiae, mouse, rat, human, rabbit, pig, bovine

manufacturer/tradename

Upstate®

technique(s)

RNA extraction: suitable (nuclear function kit)
immunocytochemistry: suitable
western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

dry ice

Application

Research Category
Epigenetics & Nuclear Function
Research Sub Category
Histones
Routinely tested by immunoblot analysis on acid extracts of HeLa cells treated with sodium butyrate.

Components

Anti-Acetyl-Histone H4 (Lys5)

Anti-Acetyl-Histone H4 (Lys 8)

Anti-Acetyl-Histone H4 (Lys 12)

Anti-Acetyl-Histone H4 (Lys 16)

Quality

routinely tested by immunoblot analysis on acid extracts of HeLa cells treated with sodium butyrate.

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

12 - Non Combustible Liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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T F Motheo et al.
Reproduction in domestic animals = Zuchthygiene, 52 Suppl 2, 103-107 (2016-12-28)
Post-translational modifications of histones, such as acetylation, are involved in regulating chromatin remodelling and gene expression. Proper in vitro maturation (IVM) of canine oocytes, for many reasons, is up to now inefficient. This study aimed to evaluate the post-translational histone
Molecular mechanism underlying the differential MYF6 expression in postnatal skeletal muscle of Duroc and Pietrain breeds.
Fan H, Cinar MU, Phatsara C, Tesfaye D, Tholen E, Looft C, Schellander K.
Gene null
Ina Theofel et al.
Biology open, 6(4), 439-448 (2017-02-27)
Male germ cell differentiation proceeds to a large extent in the absence of active gene transcription. In Drosophila, hundreds of genes whose proteins are required during post-meiotic spermatid differentiation (spermiogenesis) are transcribed in primary spermatocytes. Transcription of these genes depends
Senthil Raja Jayapal et al.
The Journal of biological chemistry, 285(51), 40252-40265 (2010-10-14)
Terminal differentiation of mammalian erythroid progenitors involves 4-5 cell divisions and induction of many erythroid important genes followed by chromatin and nuclear condensation and enucleation. The protein levels of c-Myc (Myc) are reduced dramatically during late stage erythroid maturation, coinciding
Shigeki Iwase et al.
FEBS letters, 580(13), 3129-3135 (2006-05-11)
BHC80 is a component of BRAF-HDAC complex (BHC) involved in transcriptional repression of neuron-specific genes in non-neuronal cells. However, BHC80 is present in both neuronal and non-neuronal cells. To explore the physiological importance of BHC80 in vivo, and the precise

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