Lifeink® 240 is a collagen based bioink that is suitable for 3D bioprinting using the FRESH printing technique. The recommended printing temperature is at 2-25 °C. It is a an acidic Type I collagen bioink at a concentration of 35 mg/ml. Lifeink® 240 is formulated in an acidic saline buffer solution. Once the collagen is printed into LifeSupport™, the pH and salts concentration of the printed structure become physiological. Cells can then be seeded onto the printed structure allowing for cell adherence and cellular remodeling of the 3D bioprinted structure. This bioink possesses high print fidelity, shear-thinning, strong mechanical strength, and good cytocompatibility.
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LifeSupport is a trademark of Advanced BioMatrix, Inc.
Lifeink is a registered trademark of Advanced BioMatrix, Inc.
Human autologous bioengineered skin has been successfully developed and used to treat skin injuries in a growing number of cases. In current clinical studies, the biomaterial used is fabricated via plastic compression of collagen hydrogel to increase the density and
Meniscal injuries are often associated with an active lifestyle. The damage of meniscal tissue puts young patients at higher risk of undergoing meniscal surgery and, therefore, at higher risk of osteoarthritis. In this study, we undertook proof-of-concept research to develop
In vivo remodeling of a 3D-Bioprinted tissue engineered heart valve scaffold.
Science (New York, N.Y.), 365(6452), 482-487 (2019-08-03)
Collagen is the primary component of the extracellular matrix in the human body. It has proved challenging to fabricate collagen scaffolds capable of replicating the structure and function of tissues and organs. We present a method to 3D-bioprint collagen using
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