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742031

Sigma-Aldrich

Gold nanoparticles

100 nm diameter, OD 1, stabilized suspension in citrate buffer

Synonym(s):

Au NP, Gold Colloid

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About This Item

MDL number:
MFCD00003436
UNSPSC Code:
12352302
PubChem Substance ID:
329765552
NACRES:
NA.23
Pricing and availability is not currently available.

Quality Level

100

form

nanoparticles
suspension

contains

Proprietary Surfactant as stabilizer

concentration

~3.8E+9 particles/mL

OD

1

diameter

100 nm

λmax

565-574 nm

PDI

<0.2

storage temp.

2-8°C

SMILES string

[Au]

InChI

1S/Au

InChI key

PCHJSUWPFVWCPO-UHFFFAOYSA-N

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General description

Gold nanoparticles (AuNPs) are quasi-dynamic materials that have high stability,high surface to volume ratio, high conductivity, and low toxicity. AuNPs are commercially used for various biomedical, electrochemical and energy based applications.[1][2][3][4][5]

Application

Ideal for adsorption of thiolated ligands such as oligonucleotides and polyethylene glycols. Also, due to the increased stability, these gold nanoparticles are ideal for use in physical and optical applications. Note: This product is not ideal for protein adsorption. For gold nanoparticles suitable for adsorption of proteins and other ligands for conjugate development, please see our gold nanoparticles stabilized in PBS.

This material is highly monodisperse (<12% variability in size and shape), and provides significantly improved surface reactivity. Applications include Surface Enhanced Raman Lables, Sensing/Detection, Biological Targeting, Plasmonics and Electronics.

Legal Information

Product of CytoDiagnostics, Inc.

Storage Class Code

12 - Non Combustible Liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
MKCW6833
MKCT8194
MKCS3830
MKCS5877
MKCR7075

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Gold Nanoparticles For Physics, Chemistry And Biology (Second Edition) (2012)
Gold nanoparticles for applications in energy and environment: synthesis and characterization
Chen Y
Rare Metals, 30(1), 116-120 (2011)
Spectroscopic Study of the Interaction of Carboxyl-Modified Gold Nanoparticles with Liposomes of Different Chain Lengths and Controlled Drug Release by Layer-by-Layer Technology
Kanwa N, et al.
The Journal of Physical Chemistry B, 121(50), 11333-11343 (2017)
Gold nanoparticles: preparation, properties, and applications in bionanotechnology
Yeh Y, et al.
Nanoscale, 4(6), 1871-1880 (2012)
Graphene-gold nanoparticles hybrid?synthesis, functionalization, and application in a electrochemical and surface-enhanced raman scattering biosensor
Khalil I, et al.
Materials, 9(6), 406-406 (2016)

Questions

1–10 of 14 Questions  

  1. What are the contents in citrate buffer and the concentration of each of them? Moreover, what is the PH of the citrate buffer? Or do you have any citrate buffer product is same as this stabilized suspension?

    1 answer

    1. 742031 is gold nanoparticles in citrate buffer that comes from the external supplier: CytoDiagnostics, Inc Unfortunately, the contents and concentration of components in citrate buffer is proprietary. Hence, there is no citrate buffer product guaranteed to be the same as the stabilized suspension. The vendor's SDS shows the pH of this product is 6-8: https://portal.cytodocs.com/documents/SDS/Stabilized-Gold-Nanoparticles-SDS.pdf

      Helpful?

  2. What is the viscosity and the refractive index of its citrate buffer?

    1 answer

    1. Unfortunately, the viscosity and refractive index are not test specifications for this product.

      Helpful?

  3. How to make sure the concentration of the gold nanoparticles (Particles/ml)

    1 answer

    1. The concentration is listed as a test specification on the certificate of analysis. The concentration will be a confirmed result of 3.45E+9-4.22E+9 particles/m

      Helpful?

  4. What is the shape of the gold nanoparticles?

    1 answer

    1. The majority (>95%) of the gold nanoparticles are spherical.

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  5. Which gold nanoparticle size should I choose for my application?

    1 answer

    1. The size of gold nanoparticle to use is very depandent upon the intended application. Generally, smaller particles offer better sensitivity in applications such as immunogold labeling due to less steric hindrance and the ability to bind more gold nanoparticles to the desired target. Small gold nanoparticles are less visible than larger particles, however, which must also be taken into account.As an application example, particles with a size between 30-50nm are particularly useful for the development of rapid tests such as lateral flow assays.

      Helpful?

  6. Do I need to wash my gold nanoparticles?

    1 answer

    1. For most applications, our gold nanoparticles can be used without any additional washing steps. If you have a sensitive application that requires additional washing the best way to do so is by either centrifugation or filtration.

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  7. What is the Department of Transportation shipping information for this product?

    1 answer

    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

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  8. Can the Gold nanoparticles be frozen?

    1 answer

    1. No, the Gold nanoparticles should not be frozen.  If frozen, the gold nanoparticles will irreversibly aggregate, turning the solution clear.

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  9. How does the storage temperature relate to shipping conditions?

    1 answer

    1. The storage conditions that a Sigma-Aldrich catalog and label recommend for products are deliberately conservative. For many products, long-term storage at low temperatures will increase the time during which they are expected to remain in specification and therefore are labeled accordingly. Where short-term storage, shipping time frame, or exposure to conditions other than those recommended for long-term storage will not affect product quality, Sigma-Aldrich will ship at ambient temperature. The products sensitive to short-term exposure to conditions other than their recommended long-term storage are shipped on wet or dry ice. Ambient temperature shipping helps to control shipping costs for our customers. At any time, our customers can request wet- or dry-ice shipment, but the special handling is at customer expense if our product history indicates that the product is stable for regular shipment.

      Helpful?

  10. How do you attach gold nanoparticles to oligos?

    1 answer

    1. To attach gold nanoparticles to oligos please view the information in the attached reference - Bioconjug Chem. 2011 Apr 20;22(4):794-807. Epub 2011 Mar 28.

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1–10 of 14 Questions  

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