481181
Silver(I) sulfadiazine
98%
Synonym(s):
Silver sulfadiazine, Sulfadiazine silver
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About This Item
Empirical Formula (Hill Notation):
C10H9AgN4O2S
CAS Number:
Molecular Weight:
357.14
EC Number:
MDL number:
UNSPSC Code:
12352302
PubChem Substance ID:
NACRES:
NA.23
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Quality Level
Assay
98%
form
powder
mp
285 °C (dec.) (lit.)
SMILES string
Nc1ccc(cc1)S(=O)(=O)N([Ag])c2ncccn2
InChI
1S/C10H9N4O2S.Ag/c11-8-2-4-9(5-3-8)17(15,16)14-10-12-6-1-7-13-10;/h1-7H,11H2;/q-1;+1
InChI key
UEJSSZHHYBHCEL-UHFFFAOYSA-N
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Application
Silver(I) sulfadiazine (AgSD) is popularly used for treating second-degree burn wounds as it acts as an antimicrobial agent and prevents infections. Silver sulfadiazine-impregnated polyurethane (PU) foam, chitosan/chondroitin sulfate films may be used for wound dressing.
Storage Class Code
11 - Combustible Solids
WGK
WGK 2
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Daniel J Ostlie et al.
Journal of pediatric surgery, 47(6), 1204-1207 (2012-06-19)
The 2 most commonly used topical agents for partial thickness burns are silver sulfadiazine (SSD) and collagenase ointment (CO). Silver sulfadiazine holds antibacterial properties, and eschar separation occurs naturally. Collagenase ointment is an enzyme that cleaves denatured collagen facilitating separation
Annette Downe
British journal of community nursing, Suppl, S32-S32 (2013-05-21)
This product focus seeks to give an overview of the management of wound bioburden in relation to the use of antimicrobial dressings, according to recent guidelines and best practice statements. Identification of critical colonisation/localised infection and the role of biofilms
Silver as biocides in burn and wound dressings and bacterial resistance to silver compounds.
Silver S, et al.
Journal of Industrial Microbiology, 33(7), 627-634 (2006)
Luísiane de Ávila Santana et al.
Ultrasonics, 53(4), 870-879 (2013-01-09)
The immunological mechanisms that are triggered by Low-Intensity Pulsed Ultrasound (LIPUS) in wound healing are unknown. In the present study, experimental groups were used to assess the treatment of chronic venous ulcers with 30mW/cm(2) SATA peripheral LIPUS three times per
Jason Wasiak et al.
The Cochrane database of systematic reviews, 3(3), CD002106-CD002106 (2013-04-02)
An acute burn wound is a complex and evolving injury. Extensive burns produce systemic consequences, in addition to local tissue damage. Treatment of partial thickness burn wounds is directed towards promoting healing and a wide variety of dressings are currently
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