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Key Documents

217794

Sigma-Aldrich

DL-3-Aminoisobutyric acid

98%, for peptide synthesis

Synonym(s):

α-Methyl-β-alanine

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About This Item

Linear Formula:
NH2CH2CH(CH3)COOH
CAS Number:
Molecular Weight:
103.12
Beilstein:
1720958
EC Number:
MDL number:
UNSPSC Code:
12352106
PubChem Substance ID:
NACRES:
NA.22

product name

DL-3-Aminoisobutyric acid, 98%

Quality Level

Assay

98%

form

powder

reaction suitability

reaction type: solution phase peptide synthesis

mp

179-182 °C (lit.)

application(s)

peptide synthesis

SMILES string

CC(CN)C(O)=O

InChI

1S/C4H9NO2/c1-3(2-5)4(6)7/h3H,2,5H2,1H3,(H,6,7)

InChI key

QCHPKSFMDHPSNR-UHFFFAOYSA-N

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Karima Begriche et al.
Fundamental & clinical pharmacology, 24(3), 269-282 (2009-09-09)
Beta-aminoisobutyric acid (BAIBA) is a catabolite of thymine and antiretroviral thymine analogues AZT and d4T. We recently discovered that this beta-amino acid is able to enhance fatty acid oxidation and reduce body weight in mice through an increased production of
Anja Kittel et al.
Biochemical and biophysical research communications, 430(1), 84-89 (2012-11-17)
Elevated plasma concentrations of the asymmetric (ADMA) and symmetric (SDMA) dimethylarginine have repeatedly been linked to adverse cardiovascular clinical outcomes. Both dimethylarginines can be degraded by alanine-glyoxylate aminotransferase 2 (Agxt2), which is also the key enzyme responsible for the degradation
Nailija Khajievna Spitsyna et al.
Journal of physiological anthropology and applied human science, 24(4), 345-349 (2005-08-05)
A complex anthropological survey based on population-genetic methods and a study of a wide spectrum of genetic systems (43 alleles from 17 independent loci) was undertaken among 450 Buryat women of post-reproductive age. The results obtained showed the influence of
Ts Enkhjargal et al.
Rinsho byori. The Japanese journal of clinical pathology, 52(1), 17-21 (2004-02-19)
The level of beta-aminoisobutyric acid (beta-AIB), a thymine catabolite, has been measured in urine samples of 160 healthy individuals, 28 patients with renal, 27 patients with cardiovascular and 27 patients with hematological diseases and of 36 tumor patients. No significant
Y Kurozumi et al.
Acta medica Okayama, 53(1), 13-18 (1999-03-30)
Experimental beta-alaninuria was induced in rats by injection of (aminooxy)acetate (AOA), a potent inhibitor of aminotransferases, in order to elucidate the pathogenesis of hyper-beta-alaninemia. A 27-fold increase of beta-alanine (BALA) excretion was induced by subcutaneous injection of 1 5 mg

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