V900456

L-Glutathione reduced

≥98%, Vetec^™

• Synonim(y): γ-L-Glutamyl-L-cysteinyl-glycine, GSH
• Wzór liniowy: H₂NCH(CO₂H)CH₂CH₂CONHCH(CH₂SH)CONHCH₂CO₂H
• Numer CAS: 70-18-8
• Masa cząsteczkowa: 307.32
• UNSPSC Code: 12352209
• PubChem Substance ID: 329829857
• EC Number: 200-725-4
• Beilstein/REAXYS Number: 1729812
• MDL number: MFCD00065939

Właściwości

• Nazwa produktu: L-Glutathione reduced, Vetec^™, reagent grade, ≥98%
• grade: reagent grade
• product line: Vetec^™
• assay: ≥98%
• form: powder
• technique(s): cell culture | mammalian: suitable
• color: white
• mp: 192-195 °C (dec.) (lit.)
• storage temp.: 2-8°C
• SMILES string: N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O
• InChI: 1S/C10H17N3O6S/c11-5(10(18)19)1-2-7(14)13-6(4-20)9(17)12-3-8(15)16/h5-6,20H,1-4,11H2,(H,12,17)(H,13,14)(H,15,16)(H,18,19)/t5-,6-/m0/s1
• InChI key: RWSXRVCMGQZWBV-WDSKDSINSA-N

Opis

Application

May be used at 5-10 mM to elute glutathione S-transferase (GST) from glutathione agarose.

Biochem/physiol Actions

Endogenous antioxidant that plays a major role in reducing reactive oxygen species formed during cellular metabolism and the respiratory burst. Glutathione-S-transferase catalyzes the formation of glutathione thioethers with xenobiotics, leukotrienes, and other molecules that have an electrophilic center. Glutathione also forms disulfide bonds with cysteine residues in proteins. Via these mechanisms, it can have the paradoxical effect of reducing the efficacy of anti-cancer agents.

Legal Information

Vetec is a trademark of Merck KGaA, Darmstadt, Germany

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 11 - Combustible Solids
• wgk: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable