1539905

Pioglitazone hydrochloride

United States Pharmacopeia (USP) Reference Standard

• Synonim(y): 5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-2,4-thiazolidinedione monohydrochloride
• Wzór empiryczny (zapis Hilla): C₁₉H₂₀N₂O₃S · HCl
• Numer CAS: 112529-15-4
• Masa cząsteczkowa: 392.90
• NACRES: NA.24
• PubChem Substance ID: 329750847
• UNSPSC Code: 41116107
• MDL number: MFCD04975446

Właściwości

• grade: pharmaceutical primary standard
• agency: USP
• API family: pioglitazone
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-8°C
• SMILES string: Cl.CCc1ccc(CCOc2ccc(CC3SC(=O)NC3=O)cc2)nc1
• InChI: 1S/C19H20N2O3S.ClH/c1-2-13-3-6-15(20-12-13)9-10-24-16-7-4-14(5-8-16)11-17-18(22)21-19(23)25-17;/h3-8,12,17H,2,9-11H2,1H3,(H,21,22,23);1H
• InChI key: GHUUBYQTCDQWRA-UHFFFAOYSA-N
• Gene Information: human ... PPARG(5468)

Opis

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Pioglitazone hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Pioglitazone and Metformin Hydrochloride Tablets
• Pioglitazone Tablets
• Pioglitazone and Glimepiride Tablets

Biochem/physiol Actions

Pioglitazone hydrochloride is a PPARγ agonist and thiazolidinedione (TZD) anti-diabetic.

Pioglitazone hydrochloride is a PPARγ agonist and thiazolidinedione (TZD) anti-diabetic. Pioglitazone is a selective agonist of the nuclear receptor peroxisome proliferator-activated receptor γ (PPAR-γ) and to a lesser extent PPAR-α.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

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Informacja o środkach bezpieczeństwa

• pictograms: GHS08,GHS07
• signalword: Warning
• hcodes: H302,H351
• pcodes: P202 - P264 - P280 - P301 + P312 - P308 + P313 - P405
• Hazard Classifications: Acute Tox. 4 Oral - Carc. 2
• Klasa składowania: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable