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Digoxin

United States Pharmacopeia (USP) Reference Standard

• Synonim(y): 12β-Hydroxydigitoxin
• Wzór empiryczny (zapis Hilla): C₄₁H₆₄O₁₄
• Numer CAS: 20830-75-5
• Masa cząsteczkowa: 780.94
• UNSPSC Code: 41116107
• NACRES: NA.24
• PubChem Substance ID: 329749590
• EC Number: 244-068-1
• Beilstein/REAXYS Number: 77011
• MDL number: MFCD00003674

Właściwości

• grade: pharmaceutical primary standard
• agency: USP
• API family: digoxin
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule)
• format: neat
• SMILES string: C[C@H]1O[C@H](C[C@H](O)[C@@H]1O)O[C@H]2[C@@H](O)C[C@@H](O[C@@H]2C)O[C@H]3[C@@H](O)C[C@@H](O[C@@H]3C)O[C@H]4CC[C@@]5(C)[C@H](CC[C@@H]6[C@@H]5C[C@@H](O)[C@]7(C)[C@H](CC[C@]67O)C8=CC(=O)OC8)C4
• InChI: 1S/C41H64O14/c1-19-36(47)28(42)15-34(50-19)54-38-21(3)52-35(17-30(38)44)55-37-20(2)51-33(16-29(37)43)53-24-8-10-39(4)23(13-24)6-7-26-27(39)14-31(45)40(5)25(9-11-41(26,40)48)22-12-32(46)49-18-22/h12,19-21,23-31,33-38,42-45,47-48H,6-11,13-18H2,1-5H3/t19-,20-,21-,23-,24+,25-,26-,27+,28+,29+,30+,31-,33+,34+,35+,36-,37-,38-,39+,40+,41+/m1/s1
• InChI key: LTMHDMANZUZIPE-PUGKRICDSA-N
• Gene Information: human ... ATP1A1(476), ATP1A2(477), ATP1A3(478), ATP1A4(480), ATP1B1(481), ATP1B2(482), ATP1B3(483), FXYD2(486)

Opis

General description

Find answers to frequently asked questions on USP products in USP FAQs.

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Digoxin USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Digoxin Tablets
• Digoxin Injection
• Digoxin Oral Solution

Biochem/physiol Actions

A cardiac glycoside, substrate for Pgp, upregulates Pgp expression and down regulates SXR (Steroid Xenobiotic Receptor).

A cardiac glycoside, substrate for Pgp.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

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Informacja o środkach bezpieczeństwa

• pictograms: GHS06,GHS08
• signalword: Danger
• hcodes: H300,H331,H373
• pcodes: P260 - P264 - P271 - P301 + P310 - P304 + P340 + P311 - P314
• Hazard Classifications: Acute Tox. 2 Oral - Acute Tox. 3 Inhalation - STOT RE 2
• Klasa składowania: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials