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1142107

USP

Clozapine

Name: Clozapine
Brand: USP
Price: 3230 PLN

United States Pharmacopeia (USP) Reference Standard

Synonim(y):

8-Chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo[b,e][1,4]-diazepine

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Gabaryty przesyłki	SKU	Dostępność	Cena netto
100 mg		Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności	3230,00 zł

Informacje o tej pozycji

Wzór empiryczny (zapis Hilla):

C₁₈H₁₉ClN₄

Numer CAS:

5786-21-0

Masa cząsteczkowa:

326.82

NACRES:

NA.24

PubChem Substance ID:

329749443

UNSPSC Code:

41116107

MDL number:

MFCD00153785

3230,00 zł

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Pozwól nam pomóc

grade

pharmaceutical primary standard

API family

clozapine

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

CN1CCN(CC1)C2=Nc3cc(Cl)ccc3Nc4ccccc24

InChI

1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3

InChI key

QZUDBNBUXVUHMW-UHFFFAOYSA-N

Gene Information

human ... DRD2(1813), HTR2A(3356)

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Powiązane kategorie

Analytical Reference Materials for Pharma QC

Pharmacopeia & Metrological Institute Standards

Reference Materials

Analytical Chemistry

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Ta pozycja	C2460000	BP905	1142108
USP 1142107 Clozapine	C2460000 Clozapine	BP905 Clozapine	USP 1142108 Clozapine Resolution Mixture
manufacturer/tradename USP	manufacturer/tradename EDQM	manufacturer/tradename BP	manufacturer/tradename USP
application(s) pharmaceutical (small molecule)	application(s) pharmaceutical (small molecule)	application(s) pharmaceutical pharmaceutical small molecule	application(s) pharmaceutical (small molecule)
grade pharmaceutical primary standard	grade pharmaceutical primary standard	grade pharmaceutical primary standard	grade pharmaceutical primary standard
format neat	format neat	format neat	format neat
API family clozapine	API family clozapine	API family clozapine	API family clozapine
Gene Information human ... DRD2(1813), HTR2A(3356)	Gene Information human ... DRD2(1813), HTR2A(3356)	Gene Information human ... DRD2(1813), HTR2A(3356)	Gene Information human ... DRD2(1813), HTR2A(3356)

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Clozapine USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

Clozapine Tablets

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.

Other Notes

Sales restrictions may apply.

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comparable product

Numer produktu

Opis

Cennik

1142108

Clozapine Resolution Mixture, United States Pharmacopeia (USP) Reference Standard

Y0000758

Clozapine for peak identification, European Pharmacopoeia (EP) Reference Standard

C2460000

Clozapine, European Pharmacopoeia (EP) Reference Standard

BP905

Clozapine, British Pharmacopoeia (BP) Reference Standard

pictograms

GHS06

signalword

Danger

hcodes

H301

pcodes

P264 - P270 - P301 + P310 - P405 - P501

Hazard Classifications

Acute Tox. 3 Oral

Klasa składowania

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certyfikaty analizy (CoA)

Lot/Batch Number

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Estimation of the measurement uncertainty and practical suggestion for the description of the metrological traceability in clinical laboratories.

Raúl Rigo-Bonnin et al.

Biochemia medica, 31(1), 010501-010501 (2021-01-01)

Clinicians request a large part of measurements of biological quantities that clinical laboratories perform for diagnostic, prognostic or diseases monitoring purposes. Thus, laboratories need to provide patient's results as reliable as possible. Metrological concepts like measurement uncertainty and metrological traceability

Somatostatin-expressing parafacial neurons are CO2/H+ sensitive and regulate baseline breathing.

Colin M Cleary et al.

eLife, 10 (2021-05-21)

Glutamatergic neurons in the retrotrapezoid nucleus (RTN) function as respiratory chemoreceptors by regulating breathing in response to tissue CO2/H+. The RTN and greater parafacial region may also function as a chemosensing network composed of CO2/H+-sensitive excitatory and inhibitory synaptic interactions.

Clozapine and therapeutic drug monitoring: is there sufficient evidence for an upper threshold?

Gary Remington et al.

Psychopharmacology, 225(3), 505-518 (2012-11-28)

Clozapine levels are advocated in the monitoring of patients on this drug and have now been used for a number of years. A safety-related threshold has also been proposed, as well as therapeutic lower and upper thresholds. While there has

Synthetic control of mammalian-cell motility by engineering chemotaxis to an orthogonal bioinert chemical signal.

Jason S Park et al.

Proceedings of the National Academy of Sciences of the United States of America, 111(16), 5896-5901 (2014-04-09)

Directed migration of diverse cell types plays a critical role in biological processes ranging from development and morphogenesis to immune response, wound healing, and regeneration. However, techniques to direct, manipulate, and study cell migration in vitro and in vivo in

Reintroduction of clozapine after perforation of the large intestine--a case report and review of the literature.

Saeko Ikai et al.

The Annals of pharmacotherapy, 47(7-8), e31-e31 (2013-06-13)

To report on a patient who was successfully rechallenged with clozapine after perforation of the large intestine and pulmonary embolism post operatively, and provide a literature review on clozapine rechallenge. A 46-year-old Japanese man with treatment-resistant schizophrenia developed constipation and

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Produkty

Clozapine Assay HPLC Method acc to USP Monograph

An HPLC-UV method for the identification and quantification of clozapine in API samples and tablet formulations, following the USP monograph guidelines.

Numer pozycji handlu globalnego

SKU	NUMER GTIN
1142107-100MG	04061833859667

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