V2013

[deamino-Cys¹, Val⁴, D-Arg⁸]-Vasopressin

≥95%

• Synonim(y): Val⁴−dDAVP
• Wzór empiryczny (zapis Hilla): C₄₆H₆₅N₁₃O₁₁S₂
• Masa cząsteczkowa: 1040.22
• NACRES: NA.32
• PubChem Substance ID: 329829030
• UNSPSC Code: 51111800
• MDL number: MFCD00080166
• Form: powder
• Assay: ≥95%
• Biological source: synthetic (organic)

Właściwości

• biological source: synthetic (organic)
• Quality Segment: 200
• sterility: non-sterile
• assay: ≥95%
• form: powder
• solubility: 50% acetic acid: soluble 1 mg/mL, clear, colorless
• shipped in: ambient
• storage temp.: −20°C
• SMILES string: CC(C)[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc3ccc(O)cc3)NC(=O)CCSSC[C@H](NC(=O)[C@H](CC(N)=O)NC1=O)C(=O)N4CCC[C@H]4C(=O)N[C@H](CCCNC(N)=N)C(=O)NCC(N)=O
• InChI: 1S/C46H65N13O11S2/c1-25(2)38-44(69)56-32(22-35(47)61)41(66)57-33(45(70)59-18-7-11-34(59)43(68)54-29(10-6-17-51-46(49)50)39(64)52-23-36(48)62)24-72-71-19-16-37(63)53-30(21-27-12-14-28(60)15-13-27)40(65)55-31(42(67)58-38)20-26-8-4-3-5-9-26/h3-5,8-9,12-15,25,29-34,38,60H,6-7,10-11,16-24H2,1-2H3,(H2,47,61)(H2,48,62)(H,52,64)(H,53,63)(H,54,68)(H,55,65)(H,56,69)(H,57,66)(H,58,67)(H4,49,50,51)/t29-,30+,31+,32+,33+,34+,38+/m1/s1
• InChI key: KEBRFHAVFOSSOX-WSFLLCRESA-N
• Gene Information: human ... AVPR2(554) ; mouse ... AVPR2(12000) ; rat ... AVPR2(25108)

Opis

Application

[Deamino-Cys1, Val4, D-Arg8]-Vasopressin was used to prepare sample for qualitative detection of desmopressin in plasma by using liquid chromatography-electrospray tandem mass spectrometry.

Biochem/physiol Actions

[Deamino-Pen1, O-Me-Tyr2, Arg8]-Vasopressin is a V1 antagonist that stabilizes the cardiocirculatory function in normal human as well as in patients suffering from catecholamine-resistant vasodilatory shock.It can also stimulate three acid-base transporters and hence increases the capability of the cell to regulate pHi.

Preparation Note

[deamino-Cys1, Val4, D-Arg8]-Vasopressin dissolves in water at 1 mg/ml to yield a clear, colorless solution.

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)