T7508

Tetracaine hydrochloride

≥99%, Calcium channel blocker

• Synonim(y): 4-(Butylamino)benzoic acid 2-(dimethylamino)ethyl ester, Amethocaine hydrochloride
• Wzór empiryczny (zapis Hilla): C₁₅H₂₄N₂O₂ · HCl
• Numer CAS: 136-47-0
• Masa cząsteczkowa: 300.82
• UNSPSC Code: 12352200
• PubChem Substance ID: 57654697
• NACRES: NA.77
• MDL number: MFCD00038912
• Assay: ≥99%

Właściwości

• Nazwa produktu: Tetracaine hydrochloride, ≥99%
• Quality Segment: 200
• assay: ≥99%
• solubility: chloroform: soluble 30 parts, alcohol: soluble 40 parts, H₂O: soluble mg/mL, acetone: insoluble, benzene: insoluble, diethyl ether: insoluble
• SMILES string: Cl.CCCCNc1ccc(cc1)C(=O)OCCN(C)C
• InChI: 1S/C15H24N2O2.ClH/c1-4-5-10-16-14-8-6-13(7-9-14)15(18)19-12-11-17(2)3;/h6-9,16H,4-5,10-12H2,1-3H3;1H
• InChI key: PPWHTZKZQNXVAE-UHFFFAOYSA-N
• Gene Information: human ... SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335) ;

Opis

Application

Topical ophthalmic anesthetic; used for spinal anesthesia

Tetracaine hydrochloride has been used for studying the pharmacological effects of spinal anesthesia. Tetracaine hydrochloride has also been used as a component of protease digestion buffers.

Biochem/physiol Actions

Blocks voltage-sensitive release of Ca²⁺ from sarcoplasmic reticulum.

Features and Benefits

This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Cyclic Nucleotide-Gated (CNG) and Hyperpolarization Activated Cyclic Nucleotide-Gated (HCN) Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Preparation Note

Tetracaine hydrochloride dissolves in water at 50 mg/ml to yield a clear, colorless solution. It is also soluble in 40 parts alcohol and 30 parts chloroform. However, it is practically insoluble in ether benzene or acetone.

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS06
• Słowo ostrzegawcze: Danger
• Kody zagrożeń: H301,H319,H336
• Ostrzeżenia: P261 - P264 - P271 - P280 - P301 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Oral - Eye Irrit. 2 - STOT SE 3
• Narządy docelowe: Central nervous system
• Klasa składowania: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Co się dzieje?: WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable