T2000
Testosterone β-D-glucuronide
Synonim(y):
17β-Hydroxy-4-androsten-3-one 17-D-glucuronide, 4-Androsten-17β-ol-3-one 17-glucuronide
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Informacje o tej pozycji
Wzór empiryczny (zapis Hilla):
C25H36O8
Numer CAS:
Masa cząsteczkowa:
464.55
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
Pomoc techniczna
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Pozwól nam pomócdrug control
USDEA Schedule III; Home Office Schedule 4.2; regulated under CDSA - not available from Sigma-Aldrich Canada
SMILES string
CC12CCC3C(CCC4=CC(=O)CCC34C)C1CCC2OC5OC(C(O)C(O)C5O)C(O)=O
Application
Testosterone has been used as a substrate for UDP-glucuronyltransferase based drug metabolism assays using microsome-encapsulation techniques.
Biochem/physiol Actions
Androgens direct the development of the male phenotype during embryogenesis and at puberty. Testosterone is an androgen that is secreted by the testis. This hormone is converted to dihydrotestosterone in the target tissues where it appears to mediate several biological functions.
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Klasa składowania
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.
D E Kime et al.
Ecotoxicology and environmental safety, 34(2), 165-173 (1996-07-01)
Testicular and ovarian fragments of Carassius auratus, taken during the reproductively active prespawning phase (June) of its annual reproductive cycle, were incubated with different concentrations (0 mg/ml, 0 ppm; 0.001 mg/ml, 1 ppm; 0.01 mg/ml, 10 ppm; and 0.02 mg/ml
Protein-protein interactions between UDP-glucuronosyltransferase isozymes in rat hepatic microsomes.
S Ikushiro et al.
Biochemistry, 36(23), 7154-7161 (1997-06-10)
The interactions between UDP-glucuronosyltransferase (UGT) isozymes, UGT1s and UGT2B1, in rat hepatic microsomes were investigated using an immunopurification technique with anti-peptide antibodies and a chemical cross-linking strategy. A 50 kDa protein coimmunopurified with UGT1s was identified as UGT2B1 by amino-terminal
Serena Ambrosini et al.
The Analyst, 137(1), 249-254 (2011-10-29)
Two molecularly imprinted polymers (MIPs) that we recently described to be class-selective for glucuronides have been successfully exploited for the molecularly imprinted solid-phase extraction (MISPE) of testosterone glucuronide (TG) from its parent drug (T) in urine. Both sorbents targeted the