SML3822

SA-15-P

≥98% (HPLC)

• Synonim(y): N-[4-[2-[2,5-Dimethyl-1-(phenylmethyl)-1H-pyrrol-3-yl]-2-oxoethoxy]phenyl]-2-furancarboxamide
• Wzór empiryczny (zapis Hilla): C₂₆H₂₄N₂O₄
• Numer CAS: 852846-00-5
• Masa cząsteczkowa: 428.48
• NACRES: NA.21
• UNSPSC Code: 51111800
• Assay: ≥98% (HPLC)
• Form: powder

Właściwości

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: 2-8°C

Opis

Biochem/physiol Actions

LAG-3 (CD223) inhibitor that blocks LAG-3 interactions with both major histocompatibility complex class II (MHCII) and fibrinogen-like protein 1 (FGL1).

SA-15-P is a LAG-3 (CD223) inhibitor that blocks LAG-3 interactions with both major histocompatibility complex class II and fibrinogen-like protein 1 by cell-free (MHCII IC50 = 4.21 μM & FGL1 IC50 = 6.52 μM) and cell-based binding assays (IC50 ~15 μM against 150 ng/mL or 1.5 nM FGL1-hFc binding to stable LAG-3-expressing CHO-K1 cell line).

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable