SML3061

BSJ-04-122

>97% (HPLC)

• Synonim(y): N-(2-((5-chloro-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)phenyl)acrylamide
• Wzór empiryczny (zapis Hilla): C₁₅H₁₂ClN₅O
• Numer CAS: 2513289-74-0
• Masa cząsteczkowa: 313.74
• NACRES: NA.77
• UNSPSC Code: 12352200
• Assay: >97% (HPLC)
• Form: powder

Właściwości

• Quality Segment: 100
• assay: >97% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: 2-8°C

Opis

Biochem/physiol Actions

BSJ-04-122 is a cell penetrant, potent and selective covalent inhibitor of MKK4 and MKK7 (MAP2K4/7) that binds to Cys247 of MKK4. It potently inhibits JNK phosphorylation. BSJ-04-122 exhibits antiproliferative effects against triple-negative breast cancer cells. Also, BSJ-04-122 enhances antiproliferative activity of JNK-IN-8.

cell penetrant, potent and selective covalent inhibitor of MKK4 and MKK7 (MAP2K4/7)

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable