SML1537

Cantharidin Ready Made Solution

0.1 mg/mL in DMSO

• Synonim(y): 3a,7a-Dimethylhexahydro-4,7-epoxyisobenzofuran-1,3-dione, 7a-Dimethylhexahydro-3a,4,7-epoxyisobenzofuran, Cantharidine, Hexahydro-3a,7a-dimethyl-4,7-epoxyisobenzofuran-1,3-dione
• Wzór empiryczny (zapis Hilla): C₁₀H₁₂O₄
• Numer CAS: 56-25-7
• Masa cząsteczkowa: 196.20
• UNSPSC Code: 12352200
• EC Number: 200-664-3
• NACRES: NA.77
• Form: solution

Właściwości

• biological source: insect
• Quality Segment: 200
• form: solution
• concentration: 0.1 mg/mL in DMSO
• shipped in: ambient
• storage temp.: 2-8°C
• SMILES string: O1[C@@H]2[C@]3([C@@]([C@H]1CC2)(C(=O)OC3=O)C)C
• InChI: 1S/C10H12O4/c1-9-5-3-4-6(13-5)10(9,2)8(12)14-7(9)11/h5-6H,3-4H2,1-2H3/t5-,6+,9+,10-
• InChI key: DHZBEENLJMYSHQ-XCVPVQRUSA-N

Opis

Biochem/physiol Actions

Cantharidin inhibits protein phosphatase 2A.

It is a component of mylabris, a traditional Chinese medicine. Cantharidin exhibits anti-tumor activity. In addition, cantharidin can work against multidrug-resistant cells. In the epidermis, it causes release of neutral serine proteases, leading to degeneration of the desmosmal plaque. This results in acantholysis and intraepidermal blistering as well as skin lysis. PP2A is involved in the cell cycle, cell death, growth and cell-fate determination.

Other Notes

Stable for at least two years at 2-8° C.

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 10 - Combustible liquids
• wgk: WGK 1
• flash_point_f: 188.6 °F
• flash_point_c: 87 °C